Radioprotective effect of curcumin enables it to attenuate radiation-induced inflammation and fibrosis. Understanding the mechanism of radioprotective effect of curcumin in radiation-induced PF and apoptosis can lead to the development of an effective therapeutic to combat acute lung injury and fibrosis....
by Leigh Macmillan,Vanderbilt University Radiation-induced pulmonary fibrosis—tissue scarring that can permanently impair lung function—limits the delivery of therapeutic radiation doses to non-small cell lung cancer. To develop strategies for preventing or reducingfibrosis, Michael Freeman, Ph.D., and...
treg和循环纤维细胞及其相关细胞因子在放射性肺损伤中的作用 研究 熊珊珊,徐龙,汪倩君,曹芳,孙平,王沛沛,孙丛丛,张玉可,杨婷婷,王丽男, 潘秀颉,杨陟华,朱茂祥 单位:军事医学科学院放射与辐射医学研究所邮箱地址:xss19881018@163.com 背景:放射性肺损伤为放射性肺炎和肺纤维化两阶段。肺部受损后,早期以炎症反应为主...
Y. et al. Telomerase mutations in families with idiopathic pulmonary fibrosis. N. Engl. J. Med. 356, 1317–1326 (2007). Article CAS PubMed Google Scholar Tsakiri, K. D. et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc. Natl Acad. Sci. USA 104, 7552–...
Pulmonary fibrosis (PF) is a respiratory disease characterized by fibrosis, or tissue scarring, in the lungs. To function normally, lungs need to be stretchy and elastic like a balloon in order to inflate and deflate as a person inhales and exhales. In PF, however, scar tissue causes ...
Pulmonary fibrosis is a severe and often lethal complication of the thoracic radiation used to treat cancer patients. This process is initiated by oxidative damage that precedes the onset of interstitial pneumonitis and ultimately fibrosis. The molecular pathophysiology has not been extensively defined and...
2.BACKGROUND & OBJECTIVE: Radiation pulmonary fibrosis (RPF) is characterized by fibroblast proliferation and excessive accumulation of extracellular matrix (ECM).背景与目的:放射性肺纤维化以成纤维细胞增殖和细胞外基质过度沉积为特征。 英文短句/例句 1.It was similar to the two groups in late reaction...
“Our results show that CB1 signaling plays a key pathological role in the development of radiation-induced pulmonary inflammation and fibrosis, and peripherally restricted CB1 antagonists may represent a novel therapeutic approach against this devastating complication of radiotherapy/irradiation. In summary,...
Early diagnosis of radiation-induced pulmonary fibrosis (RIPF) in lung cancer patients after radiation therapy is important. A gastrin-releasing peptide re... More by Jung Young Kim,,,Yoon-jin Lee Yoon-jin LeeDivision of Radiation Biomedical, Korea Institute of Radiological and Medical Sciences, ...
The use of this method of the model can reduce the degree of fibrosis caused by differences in surgical operations, with simple operation, low animal mortality, the more uniform distribution of lesions, but the number of administrations and the doses are larger. The modeling time is longer, ...