Define ptotic. ptotic synonyms, ptotic pronunciation, ptotic translation, English dictionary definition of ptotic. n. pl. pto·ses Abnormal lowering or drooping of an organ or a part, especially a drooping of the upper eyelid caused by muscle weakness or
释义 [医] 下垂的,上睑下垂的; 学习怎么用 权威例句 [Fixation of a ptotic kidney using lyophilised dura strips]. The hypoplastic and ptotic breast: a combined operation with prosthetic augmentation Apparatus and method for surgical correction of ptotic breasts ...
ptotic death of germ cells and Sertoli cells underlie reproductive ageing in mice and humans. In contrast to this body of work, another study has shown that in the mouse testis the necroptotic pathway is not ubiquitously expressed [33]. Others have also reported thatRipk3−/−andMlkl−...
KIDNEY stonesURATESCalcium oxalate kidney stone has become an urgent issue due to its high incidence and recurrence rate. Thus, it is necessary to explore for mechanisms of calcium oxalate stones formation. Previous studies demonstrated that oxalate crystals could induce the activation of nucleotide-...
These differences appear to be due to a decline in eWAT and iWAT mass, as there was no difference in the weights of the liver, heart, spleen, or kidney (Figure 2L) in the RSL3-treated mice compared with the vehicle-treated mice. We also found that 4-HNE staining (Figures 2M and ...
Ferroptosis promotes cyst growth in autosomal dominant polycystic kidney disease mouse models. J Am Soc Nephrol. 2021;32:2759–76. Article CAS Google Scholar Zou Y, Henry WS, Ricq EL, Graham ET, Phadnis VV, Maretich P, et al. Plasticity of ether lipids promotes ferroptosis susceptibility ...
Pyroptosis, as a lytic-inflammatory type of programmed cell death, has garnered considerable attention due to its role in cancer chemotherapy and many infl
Acute kidney injury ALI: Acute lung injury CCI: Controlled cortical impact Cox-2: Cyclooxygenase-2 DMEM: Dulbecco’s Modified Eagle’s Medium Fe2+ : Ferrous ion GBD: Global burden of disease ICV: Intracerebroventricular injection LDH: Lactate dehydrogenase MDA: Malondialdehyde miRNAs...
The role of ferroptosis in the development of acute and chronic kidney diseases. J. Cell. Physiol. 237, 4412–4427 (2022). Article CAS PubMed Google Scholar Wang, T. W. et al. Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes. Nature 611, 358–364 (2022). ...
Elevated interferon (IFN) signaling is associated with kidney diseases including COVID-19, HIV, and apolipoprotein-L1 (APOL1) nephropathy, but whether IFNs directly contribute to nephrotoxicity remains unclear. Using human kidney organoids, primary endothelial cells, and patient samples, we demonstrate...