161,162]. However, ceritinib50, is utilized in the treatment of metastatic non-small cell lung cancer [163,164] (Fig.10). Furthermore, erlotinib51, featuring a quinazoline moiety, acts as a pyroptotic agent by initiating the pyroptosis process in lung and various other tumor cells ...
In human xenograft models of kidney cancer, IL-1β regulates tumor growth and its invasiveness [65], mediated by NLRP3 activation [66]. To this end, Zhivaki et al. have shown that IL-1β was produced by hyperactive dendritic cells in a pyroptosis- independent manner, thereby enabling ...