From far, clinical and experimental data pointed to phosphate as a modulator of the parathyroid function. However, it has resulted highly difficult to state clearly a mechanism of action for phosphate on PTH secretion. Twenty-five years ago, the physiological constraints associated with the ...
ofphosphateby thekidneytubules, thereby decreasing serum phosphate concentrations. This potentiates the ability of parathyroid hormone to increase serum calcium concentrations because fewer insoluble calcium-phosphate complexes are formed when serum phosphate concentrations are low. In addition, parathyroid ...
Despite the current lack of knowledge about the function of the PTH/PTHR systems in chicken, putative PTHR activated by PTHrP were reported in chicken bone and kidney [23–25]. Studies describing the action of PTH and PTHrP on chicken tibial growth plate chondrocytes (GPCs) suggest that they...
It has been well established that soluble mediators of immune cell function including chemokines, cytokines, and several growth factors are required for the regulation of osteoblast and osteoclast activity and are also necessary for the PTH-mediated effect on bone. Monocyte chemoattractant protein-1 (M...
目的 研究老年妇女甲状旁腺激素的分泌变化以及维生素 1,2 5 (OH) 2 D3的疗效. 方法 测定 2 0例年轻妇女 (2 5～ 3 5岁 )和 2 0例老年妇女 (70～ 78岁 )血清PTH浓度 ,用RIA方法测定使用 1,2 5 (OH) 2 D3前后PTH的变化.使用RIA方法测定血清 1,2 5 (OH ) 2 D和 2 5 (OH)D的血清浓度....
With hypoxia, serum parathyroid hormone level was not changed, while urinary adenosine 3',5'-cyclic monophosphate excretion, a good parameter of parathyroid function in the kidney, was significantly decreased compared with normoxia. Based on the results of urinary adenosine 3',5'-cyclic monophhosp...
The article discusses the study "Prospective Associations of Vitamin D Status With 脽-Cell Function, Insulin Sensitivity and Glycemia: The Impact of Parath... Lee,Paul - 《Diabetes》 被引量: 9发表: 2014年 PTH-Vitamin D-Glycemia Interactions Reloaded: Figure 1 The article discusses the study ...
The patients who converted their iPTH grouping were younger, fewer of them were diabetics (p = not significant), and they were more frequently on low calcium dialysate (p < 0.05). Hyperphosphatemia was an independent risk factor for subsequent iPTH changes during the course of continuous ...
The major physiological function of parathyroid hormone (PTH) is the maintenance of Ca2+/Pi homeostasis via the parathyroid hormone/parathyroid hormone-rel... MG Barrett,GS Belinsky,AH Tashjian - 《Journal of Biological Chemistry》 被引量: 50发表: 1997年 加载更多来源...
A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells Nephrol Dial Transplant, 11 (1996), pp. 1762-1768 Google Scholar 29. P. Schwarz, H.A. Sorensen, I. Transbol, P. McNair Regulation of acute parathyroid hormone...