using cut-off levels of 6.0 mg/dL for ionized calcium, 3.0 mg/dL for phosphate, and 90 pg/mL for intact PTH, we found that 91.3% (p=0.005) , 70.7% (p=0.004) and 87.90% (p=0.023) of the patients had a positive Tc scan with their corresponding strengths of associations in the ...
The parathyroid hormone 1 receptor (PTH1R) is a class II G protein-coupled receptor which has highest levels of expression in the bone and kidney. PTH1R agonists include PTH, a hormone that plays a role in regulating blood calcium and phosphate levels, and PTH-related protein (PTHrP), a ...
Figure 1: PTH suppressive therapy and bone and vascular outcomes.Both a PTX and therapy with calcimimetics (CM) lower PTH, calcium, phosphate and FGF23 levels, albeit to a different extent, and as such, may impact on bone and vascular biolog...
Influence of sevelamer hydrochloride on serum concentration of whole (1-84) and N-terminally truncated (7-84) parathyroid hormone fragments in hemodialysis... Phosphate retention stimulates parathyroid hormone (PTH) secretion in uremic patients. Sevelamer hydrochloride is an aluminium- and calcium-free ...
The patients who converted their iPTH grouping were younger, fewer of them were diabetics (p = not significant), and they were more frequently on low calcium dialysate (p < 0.05). Hyperphosphatemia was an independent risk factor for subsequent iPTH changes during the course of continuous ...
The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia...
Stevens LA, Djurdjev O, Cardew S, Cameron EC, Levin A: Calcium, phosphate, and parathyroid hormone levels in combination and as a function of dialysis duration predict mortality: evidence for the complexity of the association between mineral metabolism and outcomes. J Am Soc Nephrol 2004;15:77...
Since parathyroid hormone regulates blood calcium and the phosphate levels, and has potent anabolic (bone-forming) effects on the skeleton, in animals (Shen, V., et al., Calcif. Tissue Int. 50:214 220 (1992); Whitefild, J. F., et al., Calcif. Tissue Int. 56:227 231 (1995) and ...
A method is disclosed whereby levels of calcium, phosphate and parathyroid hormone are measured in a patient. The patient is treated with a formulation com... T Haberberger,D Rosen,Y Kumagai 被引量: 0发表: 2011年 Parathyroid Hormone Secretion and Action: Evidence for Discrete Receptors for the...
PT cell proliferation is increased by experimental hypocalcemia or hyperphosphatemia and decreased by hypophosphatemia and administered 1,25(OH)2D3. The ... J Silver,R Kilav,A Sela-Brown,... - 《Nephrology Dialysis Transplantation》 被引量: 144发表: 2000年 ...