PhosphateParathyroid HormoneBone AluminumBone HistomorphometrySerum biochemistry related to calcium and phosphorus homeostasis and parathyroid function was studied together with bone histomorphometry after double-labeling with tetracycline and staining for aluminum in 17 patients without symptoms of bone disease,...
This reduces phosphate uptake and generates phosphaturia (high urinary phosphate). A number of molecules are involved and include FGF-23, sFRP-4, MEPE, and PTH. 2, 33, 46, 102, 105 FGF-23, PTH and sFRP-4 are all reported to impact NPT2a activity. The effects of sFRP-4 are not...
Article: The PTH-calcium relationship during a range of infused PTH doses in the parathyroidectomized rat
cell surface receptors in bone and kidney, increasing intracellular cAMP; may also function by activation of phospholipase C signal transduction pathway, inhibiting osteoclast activity; decreases Ca2+ release from bone and stimulates Ca2+ and phosphate excretion in kidneys; generally antagonistic to PTH....
OBJECTIVE:To compare the relationship between fasting serum leptin levels and body mass index (BMI) in children from different ethnic groups.#SUBJECTS:Chil... M Se,A Falorni,V Bini,... 被引量: 0发表: 2018年 加载更多来源期刊 Osteoporosis International 研究点推荐 urinary calcium phosphate excre...
Changes in estimated glomerular filtration rate (eGFR), serum fibroblast growth factor 23 (FGF23), phosphate and parathormone (PTH) lead to hypocalcaemia... BerkhofYSvanden 被引量: 0发表: 2017年 Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation Background:...
relationship between dietary magnesium intake and stroke. In both animal models and clinical studies, phosphorus intake affects the release of PTH and fibroblast growth factor-23 (FGF-23), both of which may increase oxidative stress in endothelial cells, lead to arterial calcification48and endothelial...
R. Calcium phosphate-induced renal epithelial injury and stone formation: involvement of reactive oxygen species. Kidney Int. 64, 1283–1291 (2003). Article CAS PubMed Google Scholar Colditz, G. A. The Nurses’ Health Study: a cohort of US women followed since 1976. J. Am. Med. Women...
Serum phosphate measurement is useful, the phosphate concentration being high in hypoparathyroidism, syndromes of PTH resistance and when hyperphosphataemia is the primary disturbance, and (provided renal function is adequate) low in states of abnormal vitamin D activity and/or secondary ...
andphosphate excretion, and on the other hand it increases the activity of the renal CYP27B1 (1-alpha hydroxylase)enzyme, which converts25(OH)Dto1,25(OH)2D. It was also shown that, instreptozotocin(STZ)-induced diabetic mice, the expression of PTH-related protein (PTHrP) and PTH1 ...