The kidneys were surgically removed and basolateral membranes were prepared by differential centrifugation and ultracentrifugation in discontinuous sucrose density gradients for studies of adenylate cyclase activity and hormone-receptor binding. Metabolic acidosis resulted in a significant decrease in PTH-...
of the parathyroid hormone (PTH) family (it is the N-terminal sequence of 34 amino acids of the endogenous human PTH) that promotes bone formation through its direct effect on osteoblasts, indirectly increasing calcium re-sorption by the tubules as well as phosphate excretion by the kidneys. It...
Parathyroid hormone (PTH) is produced by the parathyroid glands in response to low serum calcium concentrations where it targets bones, kidneys, and indirectly, intestines. The N‐terminus of PTH has been investigated for decades for its ability to stimulate bone formation when administered intermitten...
We note that though RGS14 action on the kidneys and Rgs14 effects on the brain share negative regulation, they involve different RGS14–Rgs14 structural features because the modulatory action of RGS14 on NPT2A-dependent phosphate transport depends on the RGS14 PDZ element, absent in rodent Rg...
What hormone would be secreted to counteract hypernatremia? a. aldosterone b. ADH Which hormone, produced by the adrenal cortex, increases sodium reabsorption in the kidneys? Which of the following is not a hormone released from the anterior...
PTH modulates bone turnover by binding to the PTH/PTH-related peptide (PTHrP) type 1 receptor (PPR), a G-protein-coupled receptor highly expressed in bone and kidneys. Osteocytes, the most abundant cells in adult bone, also express PPR. However, the physiological relevance of PPR signaling ...
PTH is the principal regulator of blood Ca concentration, acting primarily on bones and kidneys1,2. Biological actions of PTH are mediated via stimulation of the PTH type 1 receptor (PTHR1), a member of the class B family of G-protein-coupled receptors (GPCRs). PTHR1 couples strongly to...
retention of Ca^{2+} by the kidneys \\C. release of calcitriol by the kidneys \\D. increased absorption of calcium by the A skeletal disorder in adults characterized by a disturbance in bone metabolism and commonly caused by a deficienc...
PTH regulates serum calcium levels by acting mainly on bones and kidneys. Two important functions e.g. are stimulating of renal calcium re-absorption and bone resorbtion when calcium levels are low [13]. The intermittent administration of human parathyroid hormone is to date the only clinically ...
of the parathyroid hormone (PTH) family (it is the N-terminal sequence of 34 amino acids of the endogenous human PTH) that promotes bone formation through its direct effect on osteoblasts, indirectly increasing calcium re-sorption by the tubules as well as phosphate excretion by the kidneys. It...