A Case of Extremely High Intact \\{PTH\\} Levels After Total Parathyroidectomy With Auto Transplantation in a Patient on Peritoneal Dialysisdoi:10.1053/j.ajkd.2013.02.194SDOSAmerican Journal of Kidney Diseases
If your condition is mild and you have no symptoms such askidneyproblems or weakened bones, your doctor may suggest that your calcium and PTH levels be checked regularly. Medications such as cinacalcet (Sensipar)may be prescribed. Surgery may not be necessary, at least for a while....
Ten of 22 (45%) patients with chronic kidney disease stage 3 had intact PTH more than or equal to 70 pg/mL. On multivariate analysis, 25(OH) Vitamin D(3) level was negatively correlated with intact PTH (P<0.01) and alkaline phosphatase level was positively associated with intact PTH ...
Serum intact PTH was measured using the DiaSorin Liaison 1–84 PTH assay. C-telopeptide of type 1 collagen (CTx) was measured by Cobas e immunoassay analyzer ECLIA. Mean immunoassay coefficient of variation at CLS was 2.5% to 8.6% for 25(OH)D, 6.0% to 7.1% for PTH, and 3.9% to ...
Mutations in subjects with hair occur in the ligand-binding domain, leaving the DNA- binding domain intact.296 Thus, the VDR DNA-binding domain acts (through heterodimerization with RXR) in ker- atinocytes to promote hair growth without requiring bind- ing of vitamin D. This phenotypic domain...
(mg dlÀ1) Serum intact PTH (pg mlÀ1) Serum albumin (g dlÀ1) Serum urea (mg dlÀ1) Serum creatinine (mg dlÀ1) Hemoglobin A1c (%) Kt/V urea 16 62.7±15.4 — 13 (81%) 5 (31%) 7 (44%) 8 (50%) 6 (38%) 140±19 78±15 12.3±2.0 36.1±4.9 174±38 152±84 ...
The correlation of results with those of a manual assay of intact PTH was 0.97, and the results showed good agreement with disease state for patients with hypo- or hyperparathyroidism. The specificity of the assay for primary hyperparathyroidism was greater than 95%. We discuss the advantages (...
1.47 ± 0.06 mmol/liter, P = 0.002), and the postdialysis mean serum-ionized calcium was significantly higher than after the dCa++1.25 or dCa++1.5 dialyses (P = 0.002 and P = 0.003, respectively). At the beginning of the study, the concentration of plasma intact PTH ranged from 1.6 ...
Lexicon’sKlothoKO mice had poor growth and few survived past 10 weeks of age. The bone phenotype was unusual as high trabecular bone mass coexisted with low cortical bone mass102and these defects were rescued by simultaneous deletion of PTH.103These skeletal phenotypes resulted in elevated values...
In this chapter, a high-resolution mass spectrometry-based method for quantification of PTH (1-84) and its fragments is described. This method involves immunoaffinity capture of intact PTH and PTH-fragments followed by liquid chromatography-high-resolution mass spectrometry (LC-HRMS)....