In kidney cell culture, stimulation of 1伪 -hydroxylase, another mitochondrial enzyme, could be induced by GH. We are presenting the long term effect (6 months) of GH replacement (0.1u/k IM three times per week) on 25 (OH) Vit D and 1,25 (OH)2Vit D levels in 12 GH-deficient ...
Dietary Ca is an important modulator of blood pressure in humans and rats. Since the kidney plays a key role in the pathogenesis of hypertension, the effects of a low Ca diet (0.01% Ca) on blood pressure and pressure natriuresis response were studied in normotensive Sprague-Dawley rats. In ...
Influence of glucose on the toxicity of oxophenylarsine in MDCK cells On the other hand, PhAsO has been shown to inhibit glucose uptake in Madin-Darby canine kidney (MDCK) cells. We have investigated the effect of Ph... B Liebl,H Mückter,E Doklea,... - 《Archives of Toxicology》 被...
- 《Kidney International》 被引量: 69发表: 1999年 Effects of a parathyroidectomy on the immune system and nutritional condition in chronic dialysis patients with secondary hyperparathyroidism Parathyroid hormone (PTH) has an adverse effect on the immune ...
PKA inhibition eliminated the effect of DA1 agonist and partially blocked the effect of DA on NHE-3 activity. PKC inhibition did not block the DA ... MR Wiederkehr,FD Sole,R Collazo,... - 《Kidney International》 被引量: 104发表: 2001年 Modulation of voltage-dependent Ba2+ currents in...
This study was designed to identify a parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor gene polymorphism in a healthy Japanese population. All Known 13 introns of this gene were amplified by PCR, except the 1st intron, which was amplified by the long-PCR method. No restriction ...
RGS14 imparts a tonic inhibition of PTH and FGF23 actions on Pi uptake that is reversed when RGS14 is removed in the human kidney. We determined the effects of identified human genetic variants within the RGS14 PDZ ligand on NHERF1 binding and found that (Asp563Asn) disrupted the RGS14...
The guidelines proposed by the Kidney Disease Outcomes Quality Initiative (K/DOQI) suggested that intact parathyroid hormone (iPTH) should be maintained in a target range between 150 and 300 pg ml−1 for patients with stage 5 chronic kidney disease. Our study sought to verify the ...
目的:心血管疾病(cardiovascular disease,CVD)是慢性肾脏病(chronic kidney disease,CKD)最常见的严重并发症,也是导致该类患者死亡的首位病因.随着肾功能的下降,CKD患者常出现血清甲状旁腺激素(parathyroid hormone,PTH)水平异常升高的现象.既往,临床和基础研究结果已经证实,高PTH血症可诱导心脏纤维化病变和血管钙化的形成...
Effect of nutritional vitamin D preparations on parathyroid hormone in patients with chronic kidney disease Introduction Vitamin D deficiency is common and may be a risk factor for nearly all major diseases, including cancer, infections, autoimmune and cardiovasc... C Pipili,C Dimitriadis,N Sekerciog...