4H). Collectively, Thr163 PSA was associated with highest metastatic tumour burden, including bone metastases, which is consistent with our observations for the behaviour of these cells in-vitro, suggestive of a relationship with the poor prognosis of the patients, carrying the rs17632542 SNP, ...
Over the past decade, PSA has been shown to be the most valuable diagnostic and prognostic marker in oncology. However, its reliability as screening tool for PCa remains controversial due to its lack of specificity. Several non-malignant conditions of the prostate, such as BB, are associated wi...
Conclusions: The A+PSA assay represents a novel platform that integrates autoAb signatures with a conventional cancer biomarker, which may aid in the diagnosis and prognosis of prostate cancer and others. Background Both the cellular and humoral arms of the human immune system recognize tumor-...
In prostate cancer, PSA is an important biomarker for the diagnosis, treatment evaluation, and prognosis [18, 19]. An elevated serum PSA often indicates the presence and/or recurrence of prostate cancer [20] and high levels of serum PSA is typical of patients with hormone refractory prostate ...
The A+PSA assay represents a novel platform that integrates autoAb signatures with a conventional cancer biomarker, which may aid in the diagnosis and prognosis of prostate cancer and others.Background Both the cellular and humoral arms of the human immune system recognize tumor-associated antigens...
Over expression of C/EBPα in LNCaP cells was conducted with retrovirus-mediated transduction. PSA expression was examined by RT-PCR and western blot and PSA promoter activity by luciferase reporter assay. Results In normal prostate C/EBPα was expressed in the basal layer of the epithelium. In...
Materials and Methods The subjects were patients diagnosed with prostate cancer in our hospital from January 2001 to December 2008 and we examined clinical features and prognosis of the prostate cancer patients whose initial PSA were over 1000ng/ml. Results Between January 2001 to December 2008, ...
In prostate cancer, PSA is an important biomarker for the diagnosis, treatment evaluation, and prognosis [18, 19]. An elevated serum PSA often indicates the presence and/or recurrence of prostate cancer [20] and high levels of serum PSA is typical of patients with hormone refractory prostate ...
sensors Article An Ultra-Rapid Biosensory Point-of-Care (POC) Assay for Prostate-Specific Antigen (PSA) Detection in Human Serum Sophie Mavrikou 1 , Georgia Moschopoulou 1,*, Athanasios Zafeirakis 2, Konstantina Kalogeropoulou 2, Georgios Giannakos 2, Athanasios Skevis 1 and Spyridon Kintz...
An association between over- or underexpression of HSPs and prognosis has been seen for some cancers, but the prognostic impact of HSPs expression varies between tumor types, either resulting in prolonged or shortened survival [8]. Concerning Menin, its overexpression is associated with removal of...