(allP<0 05).Duringthefollow upvisit,theratioofhavingsurvivaltimeover12m and18m in thestudygroupwashigherthanthatinthecontrolgroup;thelong termcomplicationratebetweengroupsshowedno statisticallysignificantdifferences(P>0 05).Conclusions Thesimultaneouslyintegratedboostintensity modu latedradiotherapycanincreasethe...
4H). Collectively, Thr163 PSA was associated with highest metastatic tumour burden, including bone metastases, which is consistent with our observations for the behaviour of these cells in-vitro, suggestive of a relationship with the poor prognosis of the patients, carrying the rs17632542 SNP, ...
Once the pathological information is available, none of the prognostic factors known before the operation, including PSA, PSA density, and clinical, have any independent power to predict prognosis. While radical prostatectomy may carry greater risk of complications than radiotherapy, its major advantage...
Overexpres- sion of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer. Clin Cancer Res 2009;15:6398–6403. 9 Park K, Tomlins SA, Mudaliar KM, et al. Antibody- based detection of ERG rearrangement-positive pros- tate cancer. ...
In prostate cancer, PSA is an important biomarker for the diagnosis, treatment evaluation, and prognosis [18, 19]. An elevated serum PSA often indicates the presence and/or recurrence of prostate cancer [20] and high levels of serum PSA is typical of patients with hormone refractory prostate ...
Over expression of C/EBPα in LNCaP cells was conducted with retrovirus-mediated transduction. PSA expression was examined by RT-PCR and western blot and PSA promoter activity by luciferase reporter assay. Results In normal prostate C/EBPα was expressed in the basal layer of the epithelium. In...
of the all patients, 11 patients' initial PSA were over 1000ng/ml. The patients' age was 64 to 90 years old (mean age 76.1). As for the Gleason score, 5+5, 5+4 and 4+5 were one each. 4+4 were three, 3+4 were four and unknown was one patient. As for the prognosis of ...
In prostate cancer, PSA is an important biomarker for the diagnosis, treatment evaluation, and prognosis [18, 19]. An elevated serum PSA often indicates the presence and/or recurrence of prostate cancer [20] and high levels of serum PSA is typical of patients with hormone refractory prostate ...
Finally, more studies are needed to examine the association between gene methylation status and the stage and prognosis of prostate cancer. This will help avoid unnecessary treatment of some localised prostate cancers, as prostate cancer therapies are associated with significant adverse effects that ...
Briefly, 2.5 × 106 cells in 40 µL PBS were incubated on ice with 400 µL of antibody for 20 min. After incubation the mixture was transferred to an electric field of 1800V/cm and two square electric pulses were applied according to a procedure described previously [20,21] (Figure ...