Indepth look at the hypothesis of the complex-induces proximity effect (CIPE); Details on the placement of nitrogen proximal to the reactice carbonionic center.PippelDanielJ.CurtisMichaelD.HuaDuBeakPeterEBSCO_AspJournal of Organic Chemistry
ChemInform Abstract: The Complex‐Induced Proximity Effect in Organolithium Chemistry and Its Importance in the Lithiation of Tertiary Aminesorganic chemistry, reviewreactions of organo‐metal compoundsorgano‐lithium compoundsReview: 85 refs.doi:10.1002/chin.201126214...
organic chemistry, reviewmulti‐membered O,S‐heterocycles (O or S ring membersChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please...
33have also been discussed (see for instance ref.37). Here we focus on the proximity effect related to the monolayer case, where the band structure filtering effect is expected to be
Using a same batch of mice, CTTC clearly showed a higher tumor suppression effect than CTT (Supplementary Fig. 19). These in vivo results highlight the value of SNACIP in modulating endogenous undruggable targets for drug development. Discussion In summary, we introduced small molecule-nanobody ...
P. Entropic contributions to rate accelerations in enzymic and intramolecular reactions and the chelate effect. Proc. Natl. Acad. Sci. USA 68, 1678–1683 (1971). Article CAS PubMed PubMed Central Google Scholar Kirby, A.J. in Advances in Physical Organic Chemistry (eds. Gold, V. & ...
A: the effect of CheY concentration on the fluorescence anisotropy of fluorescein-labeled CheZ214FC (0.2 μM). B: Perrin plot of the fluorescence anisotropy of fluorescein-labeled CheZ214FC. The medium viscosity was increased by sucrose up to 4.6 cPoise. In this viscosity range the change in...
Magnetic proximity effect at the molecular scale First-principles calculationssu:在分子尺度上的第一原理calculationssu磁邻近效应at,帮助,the,scale,The,Scale,first,First 文档格式: .pdf 文档大小: 498.39K 文档页数: 4页 顶/踩数: 0/0 收藏人数: ...
the scintillation proximity assay (SPA) has in recent years become an important technique in high-throughput screening for drug discovery.Characterized by speed, sensitivity, reliability and the fact that no separation step is required, the main technical limitation of SPA is the `quenching effect'....
Promiscuous labeling enzymes, such as APEX2 or TurboID, are commonly used in in situ biotinylation studies of subcellular proteomes or protein–protein interactions. Although the conventional approach of enriching biotinylated proteins is widely implemen