Dna for gene expression and proteins in cellsdoi:US5607843 AThe present invention relates to an isolated nucleic acid fragment comprising a nucleic acid sequence encoding an apamin receptor protein, or biologically active fragment thereof.Patricia T. Sokol...
m6A in mRNA: an ancient mechanism for fine-tuning gene expression. Trends Genet. 33, 380–390 (2017). Article CAS PubMed Google Scholar Vu, L. P. et al. The N 6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat....
Gene expression involves transcription, translation and the turnover of mRNAs and proteins. The degree to which protein abundances scale with mRNA levels and the implications in cases where this dependency breaks down remain an intensely debated topic. H
These results suggest that lectin-sugar interactions on the cell surface of immunocompetent cells can induce cytokine gene expression and protein synthesis... K Hostanska,T Hajto,GC Spagnoli,... - 《Natural Immunity》 被引量: 151发表: 1995年 Inflammatory Mechanisms of Neurodegeneration in Toxin...
LFQ and correlation analysis detected expected proteomic differences between the whole embryo and blastomeres, and also found translational differences between individual D11 cells. LFQ on single cells raises exciting possibilities to study gene expression in other cells and models to help better ...
In terms of datasets and benchmarks, protein design is far less mature than drug discovery (paperwithcode drug discovery benchmarks). (Maybe should add the evaluation of protein design for deep learning method (especially deep generative model)) Difficulties and opportunities always coexist. Happy...
A special class of moonlighting proteins are trigger enzymes that control gene expression in addition to their enzymatic function. An example: Glyceraldehyde-3-phosphate dehydrogenase can double as uracil DNA glycosylase. Beta-sheets found in beta-keratin Three effects make Hb more suitable for ...
Objective To investigate the effect of c-fos gene silencing on differentially expressed proteins (DEPs) in human bronchial epithelial (HBE) cells after exposure to fine particulate matter (PM2.5). Methods HBE cells and c-fos-silenced HBE cells were exposed to 50 μg/mL PM2.5, LC-MS/MS and...
Evaluation of chimeric antigen receptor (CAR) expression following transduction is a critical step in the production of CAR-T and CAR-NK cells for cancer immunotherapy. To simplify CAR detection, R&D SystemsTMfluorescent-labeled proteins bind directly to single chain variable fragment (scFv) CAR T ...
Many heptahelical cell-membrane-localized receptors have been implicated in development, including the Frizzled proteins, the methuselah gene product and perhaps Smoothened. Use of knockout mice and knock-down technologies in cells enables the elucidation of the precise identity of the G proteins that ...