His serum proteinase 3-antineutrophil cytoplasmic antibody (PR3-ANCA) level was also elevated to 31.1 U/mL, but granulomatosis with polyangiitis was not observed. On the basis of the diagnosis of autoimmune cranial neuropathy, he was treated with steroid therapy. While tapering steroid therapy, his...
Proteinase 3-antineutrophil cytoplasmic antibody-(PR3-ANCA) positive necrotizing glomerulonephritis sulphasalazine treatment necrotizing glomerulonephritis segmental necrotizing glomerulonephritis PR3-ANCA-positive necrotizing glomerulonephritis ulcerative 引用走势 2012 被引量:7 0...
In most individuals, a subpopulation of neutrophils also produce CD177, proposed to present additional PR3 on the surface, resulting in CD177neg/mPR3low and CD177pos/mPR3high neutrophil subsets. A positive correlation has been shown between mPR3 abundance, disease incidence, and clinical outcome....
It was suspected that PR3-ANCA formation may have a role in COPD development, as more patients with COPD were found to be antinuclear antibody positive than healthy controls [119]. However, despite a reported association with emphysema-dominant disease and lower body mass index, no clear pathophy...
Twitter Google Share on Facebook proteinase Thesaurus Medical Encyclopedia Wikipedia Related to proteinase:Proteinase 3 pro·tein·ase (prōt′n-ās′, -āz′, prō′tē-nās′, -nāz′) n. An endopeptidase, such as pepsin, trypsin, or papain. ...
A subset of ulcerative colitis with positive proteinase-3 antineutrophil cytoplasmic antibody A small subset of patients with active ulcerative colitis is non-responsive to major known non-biological therapies. We reported 5 patients with positive s... J Xu,CH Yang,XY Chen,... - 《World Journal...
Si-Control or Si-Prtn3transfected to human CD34+ cells. Cell lysates were immunoprecipitated with anti-FLAG antibody followed by immunoblotting analysis with anti-HA or anti-FLAG antibody (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001. Data are the mean ± s.d...
In addition, we investigated whether interaction of PR3 or MPO with HUVEC monolayers also resulted in antibody-dependent cell-mediated cytotoxicity (ADCC) mediated by anti-neutrophil cytoplasmic antibody (ANCA)-positive patient sera or rabbit IgG anti-PR3 or anti-MPO. Preincubation of HUVEC monolayers...
Proteinase K, from Tritirachium album Limber 蛋白酶K 白色念球菌由来 品牌:FUJIFILM Wako CAS No.:39450-01-6 储存条件:2-10℃ 纯度:– 产品编号 (生产商编号) 等级规格运输包装零售价(RMB)库存情况参考值 160-14001 for Biochemistry100 mg– 替代品:166-28913 ...
While two PrPSc types are observed in sCJD cases (type 1 and type 2A), all vCJD cases show a unique banding pattern, referred to as type 2B, which is characterized by predominance of the diglycosylated fragment (3F4 anti-PrP antibody). (b) Western blot analysis showing conservation of ...