Third, the aqueous channel exhibits fenestrations (windows) in the walls of the pore (Figs 1and2). Such fenestrations have not been previously documented in PFTs or viroporins36,37. Similar perforations have been recently described in two different classes of ion channels, although their exact...
Similar perforations have been recently described in two different classes of ion channels, although their exact biological role remains unknown38,39. These fenestrations are partially occupied by the hydrophobic region of the lipid L1, although the dynamic nature of its acyl chains (suggested from ...