Vandenberg, J. I. and Kuchel, P. W. (2003) Nobel Prizes for magnetic resonance imaging and channel proteins. Med. J. Australia, 179, 611- 613.Vandenberg JI, Kuchel PW. Nobel Prizes for magnetic resonance imaging
In each compartment, this control is achieved through the interplay of transmembrane entry and extrusion systems (channels, exchangers, and transporters) and of buffering systems (Ca2+-binding proteins). Some of these buffers also participate in the further processing of the Ca2+ concentration signals...
A Transient Receptor Potential Channel is defined as a versatile group of ion channel proteins that respond to various external stimuli, playing critical roles in cell physiology and disease pathophysiology. They can be directly activated by stimuli or by downstream signaling components, and belong to...
Fungal pathogenMagnaporthe oryzae(M. oryzae) causes the most devastating disease that damages rice yield and grain quality worldwide.14Several blast resistance genes encoding R proteins of the nucleotide-binding leucine-rich repeat (NLR) family have been identified, and they participate in ETI.15,16...
Proteins that sense mechanical perturbations of the membrane, such as those gated by membrane tension, are prime candidates for activating in response to LIFU and thus leading to the neurological responses that have been measured. Here we use the bacterial mechanosensitive channel MscL, which has ...
Despite these genome RNA segment-coding similarities for proteins with similar functional properties, the genomes of the influenza A and B viruses also differ in coding for additional proteins that distinguish the influenza A and B virus types. For all influenza A viruses, RNA segment 7, in addit...
According to the related protein expressions measured via western blot analysis (Fig.3d), the BIP, CHOP and IRE1-α proteins are significantly upregulated in the LT/LRT-treated group, which implies the LT/LRT nanomedicines have induced ER stress in LLC cells. Subsequently, as a result of ER...
We observed an invariable co-localization of these marker proteins with TRPM5 in the respiratory system and a predominant co-localization in the duodenum. Brush cells were initially defined by morphological criteria, and a clear biological role of this cell population still remains elusive. Hypotheses...
E. et al. Rbfox proteins regulate alternative splicing of neuronal sodium channel SCN8A. Mol. Cell Neurosci. 49, 120–126 (2012). This study describes the regulation of alternative splicing of Scn8a by a neuronal transcription factor (see also Gehman et al. and Oh & Waxman). PubMed ...
Fig. 1: OEP21 is a highly positively charged β-barrel porin in the OE membrane. a, TP transport across the IE and OE membranes by the TP/Pi translocator (TPT, PDB:5Y78)40 and OE proteins (OEPs) of various sizes, such as OEP21, OEP24 and OEP37. Pi, inorganic phosphate. b, Far...