Protein tyrosine phosphatase 1B (PTP-1B) fused aromatic difluoromethane phosphonate as an inhibitorThe invention encompasses the novel class of compounds represented by the formula below, which are inhibitors of the PTP-1B enzyme. The invention also encompasses pharmaceutical compositions which include...
Protein Tyrosine Phosphatase 1B Inhibitor; 3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]-6-benzofuransulfonamide 供应商 Cayman Chemical 产品货号 15782-500 产品报价 ￥询价/500ug 产品说明书 点击查看
Compounds 1–2 possessed inhibitory activity on PTP1B enzyme with IC50 values of 26.1 ± 0.7 and 13.3 ± 0.4 μM, respectively. Ursolic acid was used as positive control showing an IC50 value of 3.5 ± 0.2 μM in this assay. This result reveals that these 9,10゛nthraquinones might be...
F. et al. Structure based design of a low molecular weight, non-phosphorous, non-peptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B. J. Biol. Chem. 275, 10300–10307 (2000).This paper describes the structure-based design of PTP1B inhibitors. CAS PubMed Google ...
& Peti, W. The mode of action of the protein tyrosine phosphatase 1B inhibitor Ertiprotafib. PLoS ONE 15, e0240044 (2020). Article CAS PubMed PubMed Central Google Scholar Erbe, D. V. et al. Ertiprotafib improves glycemic control and lowers lipids via multiple mechanisms. Mol. ...
a外卖食品商店 Outside sells the food shop [translate] aInhibition of Protein Tyrosine Phosphatase 1B by prenylated Isoflavonoids Isolated from the Stem Bar 与词根酒吧prenylated Isoflavonoids隔绝的蛋白质酚基乙氨酸磷酸酶1B的禁止 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯...
4) tyrosine kinase inhibitor 酪氨酸蛋白激酶抑制剂 1. Objective To assess the effect of tyrosine kinase inhibitor (2,5-MC) on the inhibition of in-stent inti-mal hyperplasia. 目的评估酪氨酸蛋白激酶抑制剂2,5-MC抑制支架植入术后内膜增殖的效果。 更多例句>> 5) Protein tyrosine kinase inhibitor...
Recently, a protein-tyrosine phosphatase-1B (PTP1B) inhibitor (KY-226) was developed to elicit anti-diabetic and anti-obesity effects via enhancement of insulin signaling. Previously, we reported that the nonselective PTP1B inhibitor, sodium orthovanadate, rescued neurons from delayed neuronal ...
蛋白酪氨酸磷酸酶1B(protein tyrosine phosphatase,PTP1B)是第一个被成功分离的人蛋白质酪氨酸磷酸酶(Protein Tyrosine Phosphatase PTP),它是蛋白酪氨酸磷酸酶家族中的一个经典的非受体型酪氨酸磷酸酶,在胰岛素信号通路中起着重要的负调控作用,是目前公认的一个新颖的糖尿病和肥胖症治疗靶点。 3. Studies show tha...
人PTP-1B(Protein Tyrosine Phosphatase1B)重组蛋白 瑾萱生物 更新时间:2024年07月28日 家装建材,一站式购齐,点击查看更多优质好物! 价格 ￥888.00 起订量 1支起批 货源所属商家已经过真实性核验 物流 湖北 武汉 至全国全国包邮 大小规格/种属齐全 20ug 888.00元 8888支可售 1支888.00元已选清单 ...