Genotypes were generated from blood or brain-derived DNA using microarrays (ROS/MAP and Banner) and/or whole genome sequencing (ROS/MAP and Mount Sinai Brain Bank) as described previously54,55,58. First, genotype quality control was performed on each dataset independently. Individuals with genotype...
(the globotriose blood group antigen).80Globotriose-GNPs showed size- and linker length-dependent affinity for the protein, and were used as multivalent probes for thepurificationof the B-subunit from cell lysates. The group of Kamerling has also evaluated the interaction between ConA and ...
Antimicrobial cyclic peptides effectively inhibit multiple forms ofBorreliaand cross the blood-brain barrier model Evelína Mochnáčová Katarína Bhide Mangesh Bhide ResearchOpen Access20 Feb 2025Scientific Reports Volume: 15, P: 6147 De novo design of transmembrane fluorescence-activating proteins ...
Liver cells of persons chronically infected with hepatitis B virus (HBV) shed excess hepatitis B surface antigen (HBsAg) into the blood. The HBsAg, a 22-nm lipoprotein particle antigen, has protective epitopes. To develop a vaccine, plasma was harvested from long-term chronic hepatitis B ...
It was found to be secreted from the alpha -granules of platelets activated during the coagulation of blood to form serum. Subsequent studies have demonstrated that PDGF is not one molecule but three, each a dimeric combination of two distinct but structurally related peptide chains designated A ...
Their activation requires not only the direct stimulation of foreign antigens, but also the co-stimulus signal transmitted by the interaction of surface molecules.148 The CD40/CD40L pathway is one of the most important co-stimulating pathways in T-cell activation. Because of its critical role in...
Variation in the gene encoding dysbindin-1 (i.e., dystrobrevin-binding protein 1: DTNBP1) has frequently been associated with schizophrenia. Several studies have also found that dysbindin-1 gene and protein expression are altered in two affected brain ar
Myoglobin in the urine produces a positive result on urine biochemical analysis (by reagent test strip) for blood; this must be differentiated from a positive result caused by hemoglobin. Hb F (fetal hemoglobin, the primary hemoglobin in newborns) has a P50 of 19 to 21 mm Hg, which results...
Virus-coded cell surface antigens that appear soon after the infection of a cell by virus, but before virus replication has begun. Encoded by the so-called early genes. early gene See early antigens. early growth response genes A family of cys2-his2-type zinc-finger proteins; transcription...
Improved Enzyme-Linked Immunosorbent Assay Using C-Terminal Truncated Recombinant Antigens of Babesia bovis Rhoptry-Associated Protein-1 for Detection of S... An enzyme-linked immunosorbent assay (ELISA) based on a recombinant rhoptry-associated protein-1 (RAP-1) of Babesia bovis has been previously...