Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harb Perspect Biol. 2009;1:a000950. Article PubMed PubMed Central Google Scholar Liu Y, Tavana O, Gu W. p53 modifications: exquisite decorations of the powerful guardian. J Mol Cell Biol. 2019;11:564–77...
Summary This chapter contains sections titled: Introduction What Is Protein Posttranslational Modification? Overview of Protein Posttranslational Modification Why Proteins Need to be Modified? Prokaryotic versus Eukaryotic PTM Studies of PTM Mapping of PTM Sites on RIP140 by LC–ESI–MS/MS Analysis The...
protein posttranslational modificationProteins play central and essential roles in the vast majority of biological processes. Protein function is transduced through molecular interactions involving amino acid side chains. This chapter focuses on the protein modifications that occur due to reactive species ...
post-translational modification and functional alteration of proteins at single-protein and proteomic levels16,17,18,19,20,21. Discoveries based on these methods have shed light on the importance of many PTMs in controlling protein functions,
[33,34,35,36,37]. During evolution, protein phosphorylation emerged as an essential and the most prevalent post-translational modification due to its variability and reversibility [33,35,38]. A breakthrough in the treatment of human epidermal growth factor receptor 2 (HER2) positive breast ...
Protein lipidation is a unique post-translational modification, which has the result of directly controlling the interaction of soluble protein with biological membranes affecting in turn cellular organization and trafficking. In this section we give an overview of several types of lipidation, their mecha...
[33,34,35,36,37]. During evolution, protein phosphorylation emerged as an essential and the most prevalent post-translational modification due to its variability and reversibility [33,35,38]. A breakthrough in the treatment of human epidermal growth factor receptor 2 (HER2) positive breast ...
3) post-translational modification 翻译后的蛋白质修饰4) protein modification 蛋白质修饰 例句>> 5) Chemical modification 蛋白质化学修饰6) nucleic acid/protein modified particles 核酸/蛋白质修饰补充资料:翻译后的蛋白质修饰 分子式:CAS号:性质:把某些从mRNA释译出来的蛋白质修饰加工成能被生物体细胞...
Evolution and functional cross-talk of protein post-translational modifications Mol Syst Biol, 9 (2013), p. 714 View in ScopusGoogle Scholar 21 M. Narasumani, P.M. Harrison Discerning evolutionary trends in post-translational modification and the effect of intrinsic disorder: analysis of methylation...
Post-translational modifications (PTMs) are covalent attachments of functional groups to protein substrates and play critical roles in numerous biological processes. Thus far, more than 450 PTMs on proteins have been unveiled, inclusive of phosphorylation, ubiquitination, SUMOylation, acetylation and met...