N-linked protein glycosylationWacker, MichaelNew Chemistry & New Opportunities from the Expanding Protein Universe
www.nature.com/scientificreports OPEN received: 07 June 2016 accepted: 26 September 2016 Published: 12 October 2016 Protein N-glycosylation and N-glycan trimming are required for postembryonic development of the pest beetle Tribolium castaneum Tomasz Walski1,2, Els J. M. Van Damme2, ...
1B). Low-density lipoprotein receptor-related protein 1 (LRP1, Q07954) was the most typical protein, containing as many as 21 N-glycosylation sites (Fig. S1). The average abundance of identified N-glycosylation sites on all N-glycosylated proteins was 0.4 per 100 amino acids. Figure 1 N...
Protein glycosylation continues in the Golgi apparatus by trimming and elongation of asparagine-linked oligosaccharides on glycoproteins to yield their mature forms. Trimming occurs by three mannosidases. Golgi mannosidase I removes the remaining α1,2-linked mannose residues followed by a first elongation...
Define protein glycosylation. protein glycosylation synonyms, protein glycosylation pronunciation, protein glycosylation translation, English dictionary definition of protein glycosylation. n. The addition of saccharides to proteins or lipids to form a g
Protein N-glycosylation in the baculovirus-insect cell system. One of the major advantages of the baculovirus-insect cell system is that it is a eukaryotic system that can provide posttranslational modifications, such ... Xianzong Shi, Donald L. Jarvis - 《Current Drug Targets》 被引量: 148发...
Evidence for virus-encoded glycosylation specificity. Four spontaneously derived serologically distinct classes of mutants of the Paramecium bursaria chlorella virus (PBCV-1) were isolated using polyclonal ant... I N,Wang,Li,... - 《Proceedings of the National Academy of Sciences of the United Stat...
糖基的链接分为两种:① N-连接的糖基化(N-linked glycosylation):与天冬酰胺残基的NH₂连接,连接的糖为N-乙酰葡糖胺;② O-连接的糖基化(O-linked glycosylation):与Ser、Thr和Hyp的OH连接,连接的糖为半乳糖或N-乙酰半乳糖胺,在高尔基体上进行O-连接的糖基化。
There are two main types of protein glycosylation: N-glycosylation and O-glycosylation. N-glycosylation (N-glycans attached to an aminogroup of asparagine of proteins) comprises an assembly part and a processing part, and extends over three cellular compartments: the cytosol, the endoplasmic reticulu...
Protein glycosylation can be categorized in two main types: a) N-linked glycosylation:It begins with the addition of a 14-sugar precursor to an asparagine amino acid. It contains glucose, mannose and n-acetylglucosamine molecules. This entity is then transferred to the ER lumen. The oligosaccha...