Protein may be marker for aggressive prostate cancerBritish scientists have discovered that the presence of a specific protein can distinguish between indolent and aggressive prostate cancer.Their study, ...
Image analysis workflow for immunohistochemical staining quantification. (A-D)Prostate cancer tissue microarrays were stained by immunohistochemistry. The method of image analysis performed independently for each marker was dependent on the staining pattern: default malignant epithelial area(A), malignant epit...
Spatially resolved micro proteomics for marker discovery with single cell resolution. Spatial analysis of tissue samples using MALDI MS is an emerging tool for molecular pathology because it enables discovery of diagnostically useful protein signatures that correlate with disease. An ongoing challenge is ...
We have recently identified high mobility group protein I/ Y [HMG-I(Y)], as a putative progression marker for prostate cancer (Bussemakers et al., 1991). HMG-I(Y) belongs to a family of chromosomal non-histone proteins that is composed primarily of the isoform proteins HMG-I and HMG-...
The HOXB13 gene is a member of the homeobox gene family, and prostate development depends on HOXB13 function. HOXB13 is a very sensitive and specific marker of prostate tissue and prostate cancer. When the origin of a tumor in a resection specimen or in biopsy material is unclear, it al...
The results suggest that csMVP promotes cancer progression and serves as a surface marker for mesenchymal and intermediate CTCs in patients with HCC and metastatic cancers.Similar content being viewed by others Discovery of a sushi domain-containing protein 2-positive phenotype in circulating tumor ...
We found increased levels of leptin receptor in the PR group in total plasma EVs and in a subpopulation of plasma EVs expressing the neuronal marker L1CAM. Protein restriction also shifted the phosphorylation status of the insulin receptor signal transducer protein IRS1 in L1CAM+ EVs in a ...
Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients Background To evaluate the prognostic significance of the pre-operative C-reactive protein (CRP) serum level in patients with renal cell cancer (RCC). Met... S Steffens,Astrid K?hler,R Rudolph,.....
(A) The expression of ALDOA (potential marker) was increased in CaP-RR (PC-3RR, DU145RR and LNCaPRR) cells compared with CaP (PC-3, DU145 and LNCaP) cells. β-tubulin was used as a loading control. (B) The comparison of ALDOA protein in CaP (PC-3, DU145 and LNCaP) and CaP...
Urine analysis and protein networking identify met as a marker of metastatic prostate cancer. PURPOSE: Metastatic prostate cancer is a major cause of death of men in the United States. Expression of met, a receptor tyrosine kinase, has been associat... AL Russo,K Jedlicka,M Wernick,... - ...