In CSF, 118 (p-value<0.05) and 27 proteins (q-value<0.05) were identified as significantly altered between ALS and controls. In plasma, 20 (p-value<0.05) and 0 (q-value<0.05) proteins were identified as significantly altered between ALS and controls. Proteins involved in complement ...
Neurofilaments are neuron-specific protein components of the axonal cytoskeleton8. NfL concentration in cerebrospinal fluid (CSF) has been shown to be a marker of axonal injury in several neurological disorders9,10,11. Recent evidence, published by Byrneet al., illustrates the biomarker potential of...
The binding of the non-steroidal anti-inflammatory drug indomethacin to proteins in human cerebrospinal fluid (CSF), drawn during lumbar puncture from 10 patients affected by lumbosciatica, was measured by equilibrium dialysis and spectrofluorimetry. Similar binding studies on human serum albumin ...
Cerebrospinal fluid C-reactive protein (CSF-CRP) was studied in 183 consecutive infants and children with suspected meningitis, using a nephelometric technique. Cerebrospinal fluid C-reactive protein was above an empirically chosen level of 1mg/1 in seven of 19 children with culture-proven bacterial ...
Concentration gradients in lumbar cerebrospinal fluid (CSF) for albumin and IgG were studied in 8 healthy individuals and 44 neuropsychiatric patients by serial sampling of 6 successive portions of CSF, each containing 4 ml, in all 24 ml. Significant and identical decreases between the first (0-...
To evaluate the relationship between CSF total protein concentration (CSF protein) and CSF opening pressure in idiopathic intracranial hypertension (IIH), and to explore the association of age, gender, race, BMI, and Humphrey visual field mean deviation (HVF MD) with CSF total protein. Methods ...
A screening test for IVH would be useful in those nurseries that do not have portable ultrasound capabilities and can obtain CAT-scans only with difficulty. In a previous study, RBC counts in CSF fluid have been determined not to reflect the presence or absence of IVH (Silverboard, et al....
Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. The analysis of 14-3-3 protein in cerebrospinal fluid (CSF) was shown to be highly sensitive and specific for the diagnosis of Creutzfeldt-Jakob disease (C... I Zerr,M Bodemer,O ...
Cerebrospinal fluid (CSF) τ protein levels were compared to discriminate among patients with AD, healthy controls, and patients with VaD by a meta-analysis. Patients with AD exhibit significantly higher CSF τ protein levels than healthy controls or patients with VaD in the Chinese population. ...
Do the Cerebrospinal Fluid (CSF) Glucose (GL) and Protein (PR) Values Aid Physicians (MDs) in Disposition or Treatment Decisions in the Emergency Department (ED)? 374Abbreviations: HFV, high frequency ventilationBW, body weightFIO 2 , fractional inspired oxygen...