Protein-Drug Interaction Database (PDID) addresses incompleteness of these data by providing access to putative protein-drug interactions that cover the entire structural human proteome.PDID covers 9652 structures from 3746 proteins and houses 16 800 putative interactions generated from close to 1.1 ...
Protein-Drug Interaction Database (PDID) addresses incompleteness of these data by providing access to putative protein-drug interactions that cover the entire structural human proteome.PDID covers 9652 structures from 3746 proteins and houses 16 800 putative interactions generated from close to 1.1 ...
Identifying and classifying protein interaction interfaces on a large scale can help researchers discover drug targets more efficiently. Description We introduce a large-scale protein domain interaction interface database called InterPare http://interpare.net. It contains both inter-chain (between chains...
From Chemistry to Biology Database Curation Christine Chichester, Pascale Gaudet, in Drug Discovery Today: Technologies, 2015 Protein databases are a gold mine of potential new drug targets. The ready access to a complete overview of all aspects of protein biology provides the most benefit at the...
Proteomics Project; GWAS, genome-wide association study; GERA, Kaiser Permanente Genetic Epidemiology Research on Adult Health and Aging cohort; GTEx v8, Genotype-Tissue Expression Project version 8; GEO, Gene Expression Omnibus; PPI, protein-protein interaction; DGIdb, Drug Gene Interaction Database...
GitHub - masashitsubaki/CPI_prediction: This is a code for compound-protein interaction (CPI) prediction based on a graph neural network (GNN) for compounds and a convolutional neural network (CNN) for proteins. DUD-E数据集: DUD-E: A Database of Useful (Docking) Decoys — Enhanced ...
The ProtCID database contains information on four types of interactions: protein–protein interactions at the chain level, protein–protein interactions at the domain level, domain–peptide interactions, and the interactions of domains with nucleic acids and ligands. Domain–domain interactions can be ...
Consistent with this idea, a search of a human protein–protein interaction database15 found that IRP1 interacts with Histone 2Ab51 (out of 19 reported proteins in total). In addition, we found that the presence of IRP1A in nuclei varies with tissue and nutritional conditions, raising the ...
Search options in BAInt: (a) searching the data for the interactions between the amino acid residues and bases within the distance of 4.5 Å in 1lmb and (b) partial results obtained with the search condition. Hoffman et al. (2004) created an Amino Acid–Nucleotide Interaction Database (...
profile dataset, the number of drugs whose high-confidence protein interaction information was not found in the STITCH 3.1 database, but predicted by SEA, was 533. In other words, SEA predictions contributed about 10% of the drug-protein interaction pairs in our final drug-protein interaction ...