网络释义 1. 蛋白质冠冕 ...与活细胞接触时,蛋白质会立即覆盖奈米物质表面,形成蛋白质冠冕(protein corona),在生物介质上产生一个新的生物体(biol… ehs.epa.gov.tw|基于 1 个网页
分享到: 蛋白冠 分类: 生物学词汇|查看相关文献(pubmed)|免费全文文献 详细解释: 蛋白冠(protein corona)是指纳米材料进入生物环境之后,如含血清培养基或血液等体液,其表面吸附的一层或多层蛋白所组成的结构 以下为句子列表: 分享到:
The “protein corona” consists of a variety of proteins including signaling and transport proteins, apolipoproteins, coagulation factors, adhesion mediators, or complement components, which can opsonize NP, giving it a distinctive “biological identity” [11,12]. ...
protein coronaIn biological environments, nanoparticles are enshrouded by a layer of biomolecules, predominantly proteins, mediating its subsequent interactions with cells. Detecting this protein corona, understanding its formation with regards to nanoparticle (NP) and protein proper...
The layer of protein that forms on the nanoparticle surface is called the “protein corona,” which plays a major role in interacting with biological systems. Specifically, the interactions are contingent on the surface properties of coated nanoparticles, such as the identity and amount of bound ...
, proteins) adsorb onto nanoparticles forming protein corona. Surface properties of the coated nanoparticles, in terms of type and amount of associated proteins, dictate their interactions with biological systems and thus biological fate, therapeutic efficiency and toxicity. In this perspective, we will...
The protein corona spontaneously develops and evolves on the surface of nanoscale materials when they are exposed to biological environments, altering their physiochemical properties and affecting their subsequent interactions with biosystems. In this Review, we provide an overview of the current state of...
The Protein Corona: Applications and Challenges Protein coronas can introduce new unexpected applications and shortcomings for the biomedical application of nanoparticles. For instance, it is now well recognized that the protein coating reduces the targeting capability of surface-engi... SA Alex,D ...
网络释义 1. 蛋白质环 ...附生物环境中的蛋白质分子而形成一个动态的纳米颗粒—蛋白质环(nanoparticle protein corona),学术界常以这种蛋白质 … news.sciencenet.cn|基于 1 个网页
In the first decade since the term protein corona was coined, studies have focused primarily on biomedical applications and human toxicity. The relevance of the environmental dimensions of the protein corona is still emerging. Often referred to as the eco-corona, a biomolecular coating forms upon ...