BEIJING, July 26 (Xinhua) -- Researchers from China, the United States, and Singapore have found that the accumulation of certain protein may increase the growth of cancer cells in the kidneys, providing a new therapeutic target, China Science Daily reported Thursday. Clear cell renal cell carci...
The researchers discovered that a protein called ETV4 plays a key role in how estrogen communicates with endometrial cancer cells. Estrogen sends pro-growth signals to the cells, and estrogen receptor carries out these signals. The study found that when ETV4 was removed from endometrialcancer cells...
Dietary protein, growth factors, and cancer [5] Comment on Am J Clin Nutr. 2006 Dec;84(6):1456-62. TC Campbell - 《American Journal of Clinical Nutrition》 被引量: 0发表: 2007年 Nutrition, Insulin, Insulin-like Growth Factors and Cancer The incidence of colon, pancreatic, and kidney c...
Survival and development of cancer cells without protein synthesis, however, cancer cells in the synthesis of proteins, the cells must be captured from the health asparaginase, however, coexist with asparagine-asparaginase was able to control the cancer cells growth, this is the first one it can ...
Dephosphorylation of the Retinoblastoma protein (Rb) inhibits cancer cell EMT via Zeb. Cancer Biol Ther. 2016;17:1197–205. Article CAS PubMed PubMed Central Google Scholar Cho EC, Zheng S, Munro S, Liu G, Carr SM, Moehlenbrink J, et al. Arginine methylation controls growth regulation ...
Scientists at VCU Massey Cancer Center have identified a protein that operates in tandem with a specific genetic mutation to spur lung cancer growth and could serve as a therapeutic target to treat the disease. Mutations in thep53 geneare found in more than half of all cancers, but it remains...
Cancer arises from a multitude of disorders resulting in loss of differentiation and a stem cell-like phenotype characterized by uncontrolled growth. Polycomb Group (PcG) proteins are members of multiprotein complexes that are highly conserved throughout evolution. Historically, they have been described...
SYDNEY, Oct. 26 (Xinhua) -- Australian researchers on Friday said they have identified a protein that helps trigger the growth of milk-producing mammary glands during puberty, a discovery that points to better understanding of how breast cancer develops. ...
It also strongly inhibited tumor growth as well as induced BRD4 degradation in a mouse model of JQ1-resistant triple negative breast cancer [39]. Macrocyclic PROTAC-1, a derivative of MZ1, showed strong and selective BRD4 degradation and potent anti-proliferation activity in several leukemia ...
Protein-protein interactions (PPIs) are central to a variety of biological processes, and their dysfunction is implicated in the pathogenesis of a range of human diseases, including cancer. Hence, the inhibition of PPIs has attracted significant attentio