9. Bemis TA, La Clair JJ, Burkart MD. Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras. J Med Chem. 2021 Jun 24;64(12):8042-8052.10. Troup RI, Fallan C, Baud MGJ. Current strategies for the design of PROTAC linkers: a critical review. Explor Target Antitumor ...
10. Troup RI, Fallan C, Baud MGJ. Current strategies for the design of PROTAC linkers: a critical review. Explor Target Antitumor Ther. 2020;1:273-312.
9.Bemis TA, La Clair JJ, Burkart MD. Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras. J Med Chem. 2021 Jun 24;64(12):8042-8052. 10.Troup RI, Fallan C, Baud MGJ. Current strategies for the design of PROTAC linkers:...
连接子(Linker) 2020 年10 月发布的文章《Current strategies for the design of PROTAC linkers: a critical review》中指出,PROTAC 连接子结构中最常见的是不同长度的PEG 和烷基链,分别是大约54%和31%的占比。 全球PROTAC 常用Linker结构占比 二 E3 连接酶 人...
Current strategies for the design of PROTAC linkers: a critical review [J]. Explor Target Antitumor Ther, 2020, 1(5): 273-312. 11.Anwar Z, Ali M S, Galvano A, et al. PROTACs: The Future of Leukemia Therapeutics [J]. Front Cell Dev Biol, 2022, 10: 851087. 诺和晟泰简介 成都...
9. Bemis TA, La Clair JJ, Burkart MD. Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras. J Med Chem. 2021 Jun 24;64(12):8042-8052. 10. Troup RI, Fallan C, Baud MGJ. Current strategies for the design of PROTAC linkers: a critical review. Explor Target Antitumor ...
3. PROTAC连接子相关综述:Current strategies for the design of PROTAC linkers: a critical review - PubMed (nih.gov) 4. 11月22日公布的最新ARV471临床数据:Arvinas Announces ARV-471 Achieves a Clinical Benefit Rate of 38% in Evaluable Patients and Continues to Show a Favorable Tolerability Profil...
9.Bemis TA, La Clair JJ, Burkart MD. Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras. J Med Chem. 2021 Jun 24;64(12):8042-8052. 10.Troup RI, Fallan C, Baud MGJ. Current strategies for the design of PROTAC linkers: a critical review. Explor Target Antitumor Ther...
RI, Fallan C, Baud MGJ. Current strategies for the design of PROTAC linkers: a critical review...
Current strategies for the design of PROTAC linkers: a critical review[J]. Exploration of Targeted Anti-Tumor Therapy, 2020, 1: 273-312. Zhou X, Dong R, Zhang J Y, et al. PROTAC: A promising technology for cancer treatment[J]. European journal of medicinal chemistry, 2020: 112539. ...