Evans, Jeff
c GP5 tumor samples analyzed. L/R, left or right; Apex, prostate apex; CA, cancer in primary organ; LN, lymph node; Met, metastasis. See also Additional file 1; Fig. S1. Samples with darker gray background color are from LN metastases Full size image...
Prostate cancer is comprised nearly always of adenocarcinomacells -- cells that arise from glandular tissue. Cancer cells are named according to the organ in which they originate no matter where in the body we find such cells. Thus, if prostate cancer cells spread in the body to the bones, ...
Prostate cancer is comprised nearly always of adenocarcinomacells -- cells that arise from glandular tissue. Cancer cells are named according to the organ in which they originate no matter where in the body we find such cells. Thus, if prostate cancer cells spread in the body to the bones, ...
The area of the ROI (mm2) was defined as the size of the tumor. The workflow of this study is summarized in Fig. 1. Fig. 1 A flow chart in this study workflow. PSA: prostate-specific antigen; PC: prostate cancer; DCE-MRI: dynamic contrast-enhanced MRI; DWI: diffusion-weighted ...
The randomized phase 3 CHART trial (NCT03520478) revealed that rezvilutamide (REZ) plus androgen deprivation therapy (ADT) in high-volume, metastatic, hormone-sensitive prostate cancer (mHSPC) significantly enhanced radiographic progression-free and overall survival than bicalutamide (BIC)-ADT. Accordin...
Using a simple in vitro model of os-teoblast differentiation and mineralization, we studied this interaction and observed that prostate cancer cells secreted large quantities of extracellular vesicles containing microRNAs. When ex-posed to the extracellular vesicles, increased osteoblast differentiation and ...
The 17-gene Oncotype DX® prostate cancer assay (Genomic Health Inc., Redwood City, California) is a validated, biopsy based gene expression assay that reports the Genomic Prostate Score. Combined with clinical risk features, GPS provides an individualized estimation of disease aggressiveness at dia...
FBXW2 is a poorly characterized F-box protein, as a tumor suppressor that inhibits growth and metastasis of lung cancer by promoting ubiquitylation and deg
Prostate cancer is comprised nearly always of adenocarcinomacells -- cells that arise from glandular tissue. Cancer cells are named according to the organ in which they originate no matter where in the body we find such cells. Thus, if prostate cancer cells spread in the body to the bones, ...