A flow chart in this study workflow. PSA: prostate-specific antigen; PC: prostate cancer; DCE-MRI: dynamic contrast-enhanced MRI; DWI: diffusion-weighted imaging; PZ: peripheral zone; TZ: transition zone; PI-RADS: Prostate Imaging Reporting and Data System Full size image 2.6 Statistical analys...
Prostate specific antigen(PSA) blood test: The PSA blood test measures the level of a protein found in the blood that is produced by the prostate gland and helps keep semen in liquid form. ThePSA testcan indicate an increased likelihood of prostate cancer if the PSA is at an increased or ...
Prostate specific antigen(PSA) blood test: The PSA blood test measures the level of a protein found in the blood that is produced by the prostate gland and helps keep semen in liquid form. ThePSA testcan indicate an increased likelihood of prostate cancer if the PSA is at an increased or ...
Early outcomes of active surveillance for localized prostate cancer. BJU Int. 2005;95(7):956-96015839912PubMedGoogle ScholarCrossref 9. Kattan MW, Cuzick J, Fisher G, et al; Transatlantic Prostate Group. Nomogram incorporating PSA level to predict cancer-specific survival for men with clinically...
The median age, PSA level, PSA nadir, and PSA doubling time was 65.6 years, 9.6 ng/mL, 0.03 ng/mL, and 10 months, respectively. Of the 160 men, 39 died of prostate cancer. Death from prostate cancer was far more common (78% versus 11%) and accelerated (median of 4 years versus ...
However, PSA levels can also be affected by benign prostatic hyperplasia (BPH), local inflammation or infection, prostate volume, age2, and germline genetics. In this regard, PSA is an organ—but not cancer—specific biomarker. PSA screening for PCa has been used for over 20 years, but its...
Prostate cancer (PC) is an epithelial malignancy occurring in the prostate. PC ranks second in incidence among all male malignancies globally by the latest statistics from the World Health Organization. Notably, China has seen a more rapid increase in PC incidence compared to developed European and...
Cumulative incidence curve for prostate cancer-specific mortality (PCSM) by obesity groups. overweight and 1372 (32%) were obese. A higher BMI was associated with younger age at surgery (Po0.001), lower PSA (median 7.1 vs 6.3 vs 6.1; Po0.001), and a shorter follow-up time (P = 0.050...
If the PSA level is elevated (levels can depend upon your age, on the size of your prostate gland on examination, certain medications you may be taking, or recent sexual activity) or has increased significantly over time, further testing may be needed to rule out prostate cancer. ...
In GP5, metastatic spread from prostate to pelvic lymph nodes occurred at least five separate times, by five evolutionarily distinct cancer cell populations represented by clusters Ba and Bb and their descendants (Fig. 3a). The cancer cell populations present in the left apical region of the pros...