Both patient and physician should maintain a PSA flow chart that records all PSA values, the date of measurement, and the PSA assay used. Patients with persistent elevated PSA levels may benefit from further evaluation using other PSA parameters to improve prostate cancer detection and assessment ...
PSA velocityscreeningAlthough the Food and Drug Administration recommends a prostate-specific antigen (PSA) threshold of 4 ng/dL as abnormal, investigations into the use of lower thresholds have shown substantial positive predictive value. The authors recommend that screening for prostate cancer begin ...
OBJECTIVES: To characterize testosterone profile changes over time in a cohort of prostate cancer (PCa) patients managed with active surveillance (AS) and to assess its correlation with the initial disease characteristics and further progression. METHODS: We conducted retrospective chart review of PCa ...
Read about other prostate cancer experiences. Hormone Therapy Prostate Hormone Therapy Prostate hormone therapy suppresses, blocks, or eliminates testosterone to slow the tumor’s growth. Hormone Therapy Uses Therapy can slow the tumor’s growth or lower a PSA level; it may be used before, during...
If the PSA level is elevated (levels can depend upon your age, on the size of your prostate gland on examination, certain medications you may be taking, or recent sexual activity) or has increased significantly over time, further testing may be needed to rule out prostate cancer. ...
If the PSA level is elevated (levels can depend upon your age, on the size of your prostate gland on examination, certain medications you may be taking, or recent sexual activity) or has increased significantly over time, further testing may be needed to rule out prostate cancer. ...
In both cases, plasma total PSA and several simultaneously measured percent free PSA values were available from time prior to diagnosis of prostate cancer (Fig. 7b, d). In both GP5 and GP12, no significant difference in Gleason pattern or stromal appearance was identified histologically on visual...
B7 homolog 3 (B7-H3; CD276), a tumor-associated antigen and possible immune checkpoint, is highly expressed in prostate cancer (PCa) and is associated with early recurrence and metastasis. Enoblituzumab is a humanized, Fc-engineered, B7-H3-targeting antibody that mediates antibody-dependent cel...
If the PSA level is elevated (levels can depend upon your age, on the size of your prostate gland on examination, certain medications you may be taking, or recent sexual activity) or has increased significantly over time, further testing may be needed to rule out prostate cancer. ...
Disulfidptosis refers to cell death caused by the accumulation and bonding of disulfide in the cytoskeleton protein of SLC7A11-high level cells under glucose deprivation. However, the role of disulfidptosis-related genes (DRGs) in prostate cancer (PCa) classification and regulation of the tumor...