Patients selection flow chart Full size image Table 1 Baseline Characteristics of Patients with Negative mpMRI. Full size table Univariate logistic regression analysis indicated that older age, higher PSA levels, lower f/tPSA ratio, smaller prostate volume, and higher PSAD were all significantly assoc...
For GP5, the number of tandem duplications (TDs) caused by CDK12 inactivation detected in each evolutionary cluster is shown in the table as their correlation with SBS1 mutations was used to estimate the start of the TD phenotype. b, d Age-referenced cancer subclone cladogram for each ...
To properly categorize men who had the PSA test at age 75 years or older, we used 76 years (at the time of interview) as the cutpoint for age because the survey asked whether the test occurred in the past 12 months. We categorized age into 2 groups in this ...
The interpretation of the PSA result must be done with care. PSA results must be, for example, interpreted in the context of the patient's age. Younger men (under 70 years of age and definitely under 60 years of age) may have either more aggressive prostate cancers or live long enough t...
The interpretation of the PSA result must be done with care. PSA results must be, for example, interpreted in the context of the patient's age. Younger men (under 70 years of age and definitely under 60 years of age) may have either more aggressive prostate cancers or live long enough ...
Prostatic hyperplasia (PH) is a common urologic disease that affects mostly elderly men. PH can be classified as benign prostatic hyperplasia (BPH), or prostate cancer (PCa) based on its severity. Oxidative stress (OS) is known to influence the activitie
FULL PAPER British Journal of Cancer (2014) 110, 2405–2411 | doi: 10.1038/bjc.2014.192 Keywords: active surveillance; prostate cancer; PSA screening; risk stratification Identification of pathologically insignificant prostate cancer is not accurate in unscreened men G L Shaw*,1,2, B C Thomas2,...
Analysis of factors that predict PCa on TTSB In the multivariate analysis, the factors that predicted PCa on TTSB were high age (odds ratio [OR]: 3.99, 95% confidence interval [CI]: 1.55–10.3), high PSA density (OR: 6.89, 95% CI: 2.62–18.2), low prostate volume (OR: 0.24, 95...
The interpretation of the PSA result must be done with care. PSA results must be, for example, interpreted in the context of the patient's age. Younger men (under 70 years of age and definitely under 60 years of age) may have either more aggressive prostate cancers or live long enough ...
Normal levels of serum PSA vary with age. The population median for men at age 40 is 0.6 ng/ml and by age 60 is 1.1 ng/ml15,16,17, however there are many non disease related factors which alter PSA levels such as body mass index (BMI)18,19, recent sexual activity, bicycle riding...