However, general DNase I sensitivity and DNA methylation patterns were found to be very similar in the mutated cells and in the parental cells. These findings suggest that the promoter and active transcription play a relatively limited role in maintaining transcriptionally potentiated epigenetic states....
Previously, a virus (vIVa2) expressing a 40-kDa IVa2 isoform was created. Neither the DE1/2 mutations nor the USF0 mutations could be recovered in this genetic background. These results suggest that this 40-kDa isoform can play a role in transcription....
31. In addition, the transcript cleavage factor TFS (homologous to TFIIS) transiently associates with the TEC and reactivates arrested TECs32. Spt4/5 and TFE bind to RNAP in a mutually exclusive manner and the transition from transcription initiation...
Describe the role of each of the following in transcription: a. Promoter b. Transcription Factors c. RNA Polymerase Transcription: In biological references, the term transcription generally describes the machinery wherein a section of a nucleotide base is...
The proper regulation of transcription is essential for maintaining genome integrity and executing other downstream cellular functions1,2. Here we identify a stable association between the genome-stability regulator sensor of single-stranded DNA (SOSS)3
The meaning of PROMOTER is one that promotes; especially : one who assumes the financial responsibilities of a sporting event (such as a boxing match) including contracting with the principals, renting the site, and collecting gate receipts. How to use p
In addition, motifs Flw_1 and Flw_6 were present in less than 47% of promoters, so it is possible that their TFs do not act independently at specific distances from the TLS but their role in transcription might be related to the presence of other TFs with which they act in cooperation....
2c). E–E and E–P interaction types made up the two biggest chromatin interactions in both breeds, the sum of which accounted for almost half of total chromatin interaction, indicating that enhancers played a key role in complex transcription regulation. In addition, we found that the genes...
We now show that Oct-1 binds the octamer motifs within footprints 2 and 4. Thus, Oct-1 plays a critical role in the regulation of GnRH transcription, binding functional elements in both the distal enhancer and the promoter-proximal conserved region. 展开 ...
A region of DNA initiating transcription of a particular gene. The promoter region plays a crucial role in gene expression. Promoter Meaning in a Sentence The concertpromoterannounced the lineup today. 10 She's known as a leadingpromoterof indie films. ...