Resection remains the mainstay of curative treatment with often significant waiting times. This study aims to quantify the T-stage progression and growth of non-small cell lung cancers (NSCLCs) between radiological diagnosis and resection, and its impact on disease recurrence and survival.McPherson,...
and challenging clinical problem. although evidence-based guidelines and decision analytic models have been developed to help guide clinical decisions about diagnosis and treatment of patients with spn, these tools are limited by gaps in our current knowledge about the natural history of lung cancer. ...
Lung cancer is one of the most commonly diagnosed cancers and a leading cause of cancer related mortality [1]. The global incidence and mortality of lung cancer is increasing significantly [2]. In addition to environmental exposures such as smoking, the growth factor pathway and hormonal regulatio...
OBJECTIVE: To study the initial findings of lung adenocarcinoma revealed by computed tomography (CT) scanning and observe tumor progression and elucidate appropriate follow-up schedule of tumor diagnosis via CT findings of suspected lung adenocarcinoma. METHOD: We studied 59 patients who had undergone ...
Other variables, such as molecules, can also act as prognostic factors for evaluating the recurrence or progression of the disease. Examples of these include alfa-fetoprotein (AFP) levels in hepatocellular carcinoma [9], prostate-specific antigen (PSA) levels in prostate cancer [10], and so on...
Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the role of circFLNA in the progression of lung cancer. The target gene of circFLNA was determined by bioinf
Hi, I must say that it is a pity she didn’t notice it before, while she could prevent spreading of the cancer by therapy or even if necessary removing the infected to prevent any new malignant occurrence. The metastatic activity of a tumor, increases with both tumor size and nodal involv...
Table 2 Tspan protein family as a biomarker in cancer diagnosis. Full size table The role of the Tspan protein family in cancer treatment Table 3 The role of the Tspan protein family in cancer treatment. Full size table The role of the Tspan protein family in drug therapy ...
MALAT1 is well documented to be highly expressed in non-small cell lung cancer (NSCLC) and its overexpression closely associates the malignant phenotype of NSCLC cells and poor prognosis of NSCLC patients. MALAT1 is also identified to enhance β-catenin expression and under the negative regulation...
Globally, gastric cancer (GC) is a leading cause of cancer death [1], but despite declining morbidity and mortality rates in recent decades, high metastasis rates generate poor prognosis outcomes for GC [2]. In particular, for advanced GC, successful early diagnosis and surgical resection rates...