Lung cancer is the leading cause of cancer-related death in the world. To understand the molecular processes and pathways of, and contributing factors to lung cancer progression, genetic alterations in various progression stages of lung cancer cells have been studied, since these alterations can be...
Cancerous tissues comprise a wide variety of cells in addition to tumor cells, such as immune cells, fibroblasts1, endothelial cells2, and neural cells3, which constitute unique microenvironments specific to the cancer cell type. In particular, different types of immune cells have been demonstrated...
Lung cancer is one of the most commonly diagnosed cancers and a leading cause of cancer related mortality [1]. The global incidence and mortality of lung cancer is increasing significantly [2]. In addition to environmental exposures such as smoking, the growth factor pathway and hormonal regulatio...
et al. Factors influencing ten-year survival in resected stages I to IIIa non-small cell lung cancer. J. Thorac. Cardiovasc. Surg. 117, 32–36 (1999). CAS PubMed Google Scholar Maeda, R. et al. Long-term outcome and late recurrence in patients with completely resected stage IA non-...
to differentiate into cancer cells and a variety of stromal cells, maintaining the csc microenvironment to promote csc properties and tumour development. cscs can differentiate into cancer cells, which has been validated in other types of cancers, including pancreatic, prostate, lung and liver cancer...
Hi, I must say that it is a pity she didn’t notice it before, while she could prevent spreading of the cancer by therapy or even if necessary removing the infected to prevent any new malignant occurrence. The metastatic activity of a tumor, increases with both tumor size and nodal involv...
Gastric cancer is one of the leading causes of cancer-related death around the world [1]. In spite of improvement in surgery, chemotherapy, and radiotherapy, the outcome of gastric cancer patients at advanced stages still remains poor, mainly due to tumor recurrence, invasion, and metastasis [...
Ovarian cancer (OC) is distinguished by its aggressive nature and the limited efficacy of current treatment strategies. Recent studies have emphasized the significant role of cancer-associated fibroblasts (CAFs) in OC development and progression. Employi
B. et al. A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors. Cell 185, 3807–3822.e12 (2022). Article CAS PubMed Google Scholar Cho, I. & Blaser, M. J. The human microbiome: at the interface of health and disease. Nat. Rev. Genet. 13, ...
Lung cancer remains the primary cause of cancer-related deaths globally, with lung adenocarcinoma (LUAD) being its most dominant histological subtype1,2. Despite considerable progress in therapeutic approaches for LUAD, particularly with the introduction of immunotherapy, the prognosis remains less than...