Symptoms of Glioblastoma Multiforme Glioblastoma Multiforme is a type of aggressive tumor that grows and damages the nearby nerves and brain tissues causing temporary or permanent impairment of vision, hearing, memory, movement and thoughts. Sometimes, the tumor causes swelling in the brain that leads...
Objective Glioblastoma multiforme (GBM) is the most common malignant and aggressive primary brain tumor. The standard therapy is a multi-modality approach which includes maximal safe surgical resection of the tumor and subsequent radiotherapy with concomitant and adjuvant chemotherapy. Although the survival...
According to a 2003study, glioblastoma multiformeprognosiscan be divided into three subgroups dependent on KPS, the age of the patient, and treatment. WikiMatrix We are very concerned at thisprognosis, which is based onstudiesthat need to be further researched and deepened, rather than hidden and...
98. The method of claim 97, wherein the method of quantifying the expression level of the at least two genes or gene expression products comprises the use of at least one assay selected from the group consisting of real-time quantitative PCR, microarray analysis, Nanostring, RNA sequencing, N...
The screened lncRNAs were pairwise paired and combined with clinical data, and finally, a signature was constructed by Lasso regression and Cox regression in 13 pairs of DEIRlncRNAs. According to the Akaike information criterion (AIC) values of the 1-year receiver operating characteristic curve, ...
Glioblastoma multiforme: evidence-based approach to therapy. Glioblastoma multiforme (GBM) is the most aggressive of the infiltrating gliomas. Standards of care for treatment continue to evolve. In many westernized c... MK Nicholas - 《Expert Review of Anticancer Therapy》 被引量: 78发表: 2007年...
Prognostic markers for glioblastoma are lacking. Both intrinsic tumour characteristics and microenvironment could influence cancer prognostic. The aim of our study was to generate a pure glioblastoma cell lines and immune classification in order to decipher the respective role of glioblastoma cell and micr...
Intra-tumoral heterogeneity and cell-state plasticity are key drivers for the therapeutic resistance of glioblastoma. Here, we investigate the association between spatial cellular organization and glioblastoma prognosis. Leveraging single-cell RNA-seq and spatial transcriptomics data, we develop a deep learn...
The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of he
Among these, grade IV gliomas, also known as glioblastoma multiforme (GBM), exhibit the highest degree of growth aggressiveness2. Unfortunately, despite advances in diagnosis and drug therapy, glioblastoma remains incurable, with a median survival time of 15 months and a 5-year survival rate of ...