Stage 4 glioblastoma multiforme Life expectancy Stage 4 glioblastoma multiforme is the last stage of brain tumor. For the patient in IV stage of glioblastoma multiforme, the rate of survival diminishes. With treatment, the patient can hardly live two years as the disease is not curable. In thi...
Prognosis classification in glioblastoma multiforme using multimodal MRI derived heterogeneity textural features: impact of pre-processing choices. In: Pro- ceedings of Medical Imaging 2016: Computer-Aided Diagnosis; 2016 Mar 24; San Diego, CA. Bellingham, WA: SPIE; 2016...
Glioblastoma multiforme (GBM) is a debilitating disease that is associated with poor prognosis, short median patient survival and a very limited response to therapies. GBM has a very complex pathogenesis that involves mutations and alterations of several key cellular pathways that are involved in cell...
A previous study reported that high CD33 levels confer a poor prognosis for GBM patients [43]. In our study, high CD33 and low BATF2 expression were observed in tissue samples from GBM patients in advanced clinical stages. MDSCs are divided into two distinct subsets based on the expression o...
across glioblastoma phases and functional analyses offered insights into the role of genes. These findings support the development of more accurate and personalized prognostic tools and gene-based therapies that improve the survival and quality of life of individuals afflicted by glioblastoma multiforme. ...
Dai2†, Meng‑Yuan Yin1,2, Hong‑Wei Cheng2*, Hai‑Sheng Qian1, Hua Wang3, Dao‑Ming Zhu4* and Xian‑Wen Wang1* Abstract Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is associated with poor prognosis....
Glioblastoma (GBM) is a highly aggressive malignant primary brain tumor, characterized by rapid growth, diffuse infiltration of cells into both adjacent and remote brain regions, and a generalized resistance to currently available treatment modalities. R
Despite numerous reports indicating the significant impact of RNA modification on malignant glioblastoma (GBM) cell behaviors such as proliferation, invasion and therapy efficacy, its specific involvement in glioblastoma (GBM) angiogenesis is remains unc
Cell-to-cell communication is essential for the development and proper function of multicellular systems. We and others demonstrated that tunneling nanotubes (TNT) proliferate in several pathological conditions such as HIV, cancer, and neurodegenerative
Increased EGFR expression and activity- both as a response to external stimuli or due to a gain-of-function mutation- correlate with an exceptionally poor prognosis in human GBM patients. To determine whether EGFR signaling regulates STAT6 activity in our GBM cells, we treated U-1242MG and U-...