PROCESS FOR GENE EXPRESSION IN E COLI WITH THE HELP OF A SYNTHETIC REGULATORY REGION1. Claims (for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL and SE) A synthetic regulation region for the expression of heterologous genes in E. coli, containing a promotor, a ...
A synonymous mutation in IGF-1 impacts the transcription and translation process of gene expression Author links open overlay panelS.Y. Wang 1 3 4, Y.Y. Cheng 2 4, S.C. Liu 1 4, Y.X. Xu 1, Y. Gao 1, C.L. Wang 1, Z.G. Wang 1, T.Q. Feng 1, G.H. Lu 1, J. Song...
the molecular mechanism governing the gallic acid-induced cancer cell death process is largely unclear, thus hindering development of novel therapeutics. Therefore, we performed time-course RNA-sequencing to reveal the gene expression profiles at ...
Accessible chromatin regions allow for the selective binding of regulatory elements, which is crucial to regulate gene expression in cell-type-specific or context-specific manners60. To explore potential mechanisms governing the transcriptional dynamics of microglia across the lifespan, we mapped the ...
We evaluated the expression profiles of turbot in spleen, liver, and head kidney across five temporal points of the Philasterides dicentrarchi infection process using an 8x15K Agilent oligo-microarray. The microarray included 2,176 different fivefold replicated gene probes designed from a turbot 3...
RNA transcriptionor simply stated as transcription is the first step of gene expression. Transcription is the process by which a DNA sequence contained in the gene is copied in the form of an RNA molecule (a single-stranded molecule made up of RNA nucleotides). The product of transcription cal...
Methods for modulating expression of a gene are provided. The methods comprise the steps of selecting a portion of an RNA coded by the gene, wherein the RNA is capable of interacting with a protein, preparing an oligonucleotide or oligonucleotide analog to mimic the portion of the RNA, and ...
Dirichlet Process Mixture Model for Correcting Technical Variation in Single-Cell Gene Expression Data We introduce an iterative normalization and clustering method for single-cell gene expression data. The emerging technology of single-cell RNA-seq gives ac... S Prabhakaran,E Azizi,A Carr,... - ...
Studies on the regulation of gene expression in eukaryotes in the past 20 years have consistently revealed increasing levels of complexity. Thirty years ago it seemed that we had understood the basic principles of gene regulation in eukaryotes. It was thought that regulation of transcription was the...
cells, in each region. However, some tissue-specific effector genes begin to be expressed in parallel with the expression onset of early specification genes, raising questions about the simplistic regulatory scheme of tissue-specific effector gene expression and the current concept of differentiation ...