Across multiple courses, we also found that lopinavir and ritonavir, known COVID-19 drugs, participate in changing calcium ion concentrations during ER stress, which can also lead to inflammation. Moreover, the sub-process ‘negative regulation of SERCA gene expression’ can cause ‘negative regulat...
Calcium RadioisotopesMuscle ContractionStimulation, ChemicalCecumThe effect of readmitted Na on the Ca-depletion process in the carbachol-sensitive Ca-store was investigated using thin bundles of the K-depolarized, Na-depleted guinea-pig taenia caecum. To estimate the quantity of stored Ca, the "Ca-...
while it is being formed or is in the reversal phase from bone resorption to bone formation at other site. This implies that there is continuous focal transient loss of bone that is fully reversed in balanced remodeling; as the number of activated remodeling sites increases...
Calcium (Ca2+) homeostasis is essential for neuronal function and survival. Altered Ca2+homeostasis has been consistently observed in neurological diseases... K Lee,S Huh,S Lee,... - 《Proceedings of the National Academy of Sciences of the United States of America》 被引量: 0发表: 2018年 ...
Yu Z, Luo H, Fu W, Mattson MP: The endoplasmic reticulum stressresponsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp Neurol. 1999, 155: 302-314. 10.1006/exnr.1998.7002. Article CAS PubMed Google...
To further elucidate the composition of the dominant elements in peri-implant bone, the EDX was used to analyze the elemental content of calcium, phosphorus, oxygen and carbon. The calcium and phosphorus content of peri-implant bone were lower in the compressive side than that in the tensile si...
申请(专利权)人: WARNER-LAMBERT COMPANY 发明人: S Dieter,M Lin 摘要: A novel process for the preparation of amorphous atorvastatin is described where crystalline Form I atorvastatin is dissolved in a non-hydroxylic solvent and after removal of the solvent affords amorphous atorvastatin.收藏...
reticulum (ER) is a critical site for protein, lipid, and glucose metabolism, lipoprotein secretion, and calcium homeostasis36. Previous research has demonstrated that intracellular triglyceride droplets, known as cytoplasmic lipid droplets, are secreted into milk as plasma membrane bilayer-coated ...
(t-SNAREs) associated at the base of porosomes [4], and synaptic vesicle-associated protein VAMP or v-SNARE, interact in a circular array [7] to form conducting channels in the presence of calcium [7,12]. During cell secretion, swelling of secretory vesicles result in a build-up of ...
Calcium phosphates (CaP), especially hydroxyapatite, are the most commonly used bioceramics because their main component exhibits a similarity to the minerals found in natural bone and they provide osteoconductive characteristics that allow formation of a tight connection with surrounding bone tissues [9]...