pro-inflammatory molecules 促炎性分子
such as the mitochondrial microprotein BRAWNIN [33], while others are unique to a single species, like those found in yeast [34]. This variability is particularly evident
many microproteins might be short lived but can have a function because they are processed and presented as HLA epitopes for immune cell signaling [19
These findings indicate that markers of a pro-inflammatory state vary continuously with the BMI, suggesting that adiposity of any degree, even if considered to be within the normal range, is associated with detectable levels of pro-inflammatory molecules. Whether these have clinical significance will...
The meaning of PRO-INFLAMMATORY is promoting inflammation : capable of causing inflammation. How to use pro-inflammatory in a sentence.
TNF-α Like other Th1 pro-inflammatory cytokines, TNF-α has an important role comprising the inflammatory response both locally and in the circulation. TNF-α triggers the expression of vascular endothelial cells as well as enhances the leukocyte adhesion molecules th...
Interestingly, p38MAPK which induced pro-inflammatory molecules in ALS pre-treated MΦs is also one of the key molecules that participate in phagosomal maturation40,41and attenuateLeishmaniagrowth within the host MΦs40. In order to ascertain the role of p38 MAPK in phago-lysosome fusion in our...
TNF-α plays a vital role in the upstream initiation stage of the inflammatory cascade response. It is a crucial cytokine in the Th1 signaling pathway. It can induce glial and vascular endothelial cells to express cell adhesion molecules (ICAM-1), promoting the migration of activated neutrophils...
These molecules have been previously implicated in the chemotaxis and activation of microglia in high-grade glioma. Specifically, the hyaluronic acid receptor CD44 can interact with microglial osteopontin (SPP1) and is related to glioma tumor growth36; IL-6 has been associated with myeloid cell ...
My research has proven that human lung fibroblastic cells are also responsive to the fibrinopeptide, and under its influence, will express selective pro-inflammatory molecules on the cell surface and will secrete pro-inflammatory mediators, such as cytokines and chemical attractants for immune cells...