pro-inflammatory molecules 促炎性分子
Pro-inflammatory molecules such as IFN-γ, TNF-α, IL-1β, synergistically increase IDO activity and tryptophan consumption. In contrast, anti-inflammatory cytokines IL-4 and IL-10 inhibit the IDO-mediated tryptophan catab 正在翻译,请等待... [translate] ...
Interestingly, p38MAPK which induced pro-inflammatory molecules in ALS pre-treated MΦs is also one of the key molecules that participate in phagosomal maturation40,41and attenuateLeishmaniagrowth within the host MΦs40. In order to ascertain the role of p38 MAPK in phago-lysosome fusion in our...
Using high-resolution metagenomics, we highlighted gut microbiome signatures (dysbiosis) in allergic children and strain-level adaptation in allergy, withR. gnavusemerging as likely involved in the pathogenesis of allergic disease. We also suggest that the production of pro-inflammatory molecules and the...
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Suppression of pro-inflammatory adhesion molecules by PPAR-delta in human vascular endothelial cells 2008. Suppression of pro-inflammatory adhesion molecules by PPAR-δ in human vascular endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28... Y Fan,Y Wang,Z Tang,... - 《...
A range of other cell-surface cellular and junctional adhesion molecules were basally expressed by the hCMVEC but were unaffected by IL-1β or TNFα.To our knowledge, this is the most comprehensive analysis of the immunological profile of brain endothelial cells and the first direct evidence ...
Cytokines are pleiotropic molecules with important roles in inflammatory responses. Pro-inflammatory cytokines and neuroinflammation are important not only in inflammatory responses but also in neurogenesis and neuroprotection. Sustained stress and the subsequent release of pro-inflammatory cytokines lead to chr...
Furthermore, we evaluated the effects of ferritin, FeH, and FeL on human macrophages, assessing pro- and anti-inflammatory cytokines, and expression of NLRP3. Finally, we checked the ability of macrophages, which were stimulated with these molecules, to enhance or not the proliferation of ...
In the corneal alkali burn injury model, various NLRP3 inflammasome-related molecules were up-regulated, and NLRP3 knockout led to significant reduction of corneal opacity, neutrophil infiltration, and expression of pro-inflammatory molecules including MMP-9. Similar up-regulation of NLRP3 inflammasome...