Elevated levels of 32 proteins were positively associated with the FI, cross‐sectionally at all ages (range: β‐coefficients 0.22–2.06; FDR 0.021–0.024), of which 18 were also associated with frailty status (range: odds ratios 1.40–5.77; FDR 0.022–0.016). Based on the accrued data, ...
The role of myelodysplastic syndrome-related inflammatory proteins in endogenous erythropoietin regulation and response to erythroid-stimulating agents or lenalidomide has not been investigated. The HepG2 hepatoma cell line was used to investigatein vitroerythropoietin elaboration. Serum samples collected from...
and granulocytes. IL-6 stimulates several types of leukocytes and the production of acute phase proteins in the liver. It is particularly important in inducing B-cells to differentiate into antibody-forming cells (plasma cells). Binding of IL-6 to its receptor init...
期刊PLoS One 时间2012 影响因子3.041 起止号7(7):e40156. 种属Canine,Human,Non-Human Primate 技术平台MSD 样本类型Cell culture supernatants 研究方向免疫/内分泌 细胞类型其它细胞 检测蛋白IL-8 相关货号 LXMH04-2LXMH04-4LXMH07-4LXMH09-1LXMH09-3LXMH10-1LXMH10-3LXMH10-9LXMH11-1LXMH111-1LXM...
Changes to immunomodulatory proteins were minimal, with IL-12(p70), IL-13 and VEGF significantly lower in mild endometriotic women compared to non-endometriotic women (−39%, −54% and −76% respectively). Verification using C-reactive protein as a non-specific marker of inflammation ...
After stimulation of macrophages with ferritin, for 120 and 240 min, the proteins expression of IL-1β, NLRP3 and IL-12 remained unchanged when compared to UT cells (Fig. 4). Interestingly, when macrophages were stimulated with FeH for 240 min, the levels of proteins expression of IL-1β...
In addition, CD11c~+ ATMs were enriched for mitochondria and for RNA transcripts encoding mitochondrial, proteasomal, and lysosomal proteins, fatty acid metabolism enzymes, and T-cell chemoattractants, whereas CDllc~- ATMs were enriched for transcripts involved in tissue maintenance and repair. Tissue...
Total proteins from cell lysates and culture media were separated by 2-dimensional gel electrophoresis (2-DE), and differentially expressed proteins were identified by MALDI-TOF MS and MS/MS. Dendritic cell-derived IFN-gamma-induced protein (DCIP) was found up-regulated by TNF-alpha in lung ...
Cytokines, Acute-Phase Proteins, and Hormones The cytokine network is a homeostatic system that has to be perceived in an analogous fashion to the acid/base equilibrium. The level of any cytokine in bi... D Burger,Jean-Michel Dayer - 《Annals of the New York Academy of Sciences》 被引量...
(Fig.1f), unless otherwise specified. As expected, treatment with LPS + IFNγ upregulated the M1 genes and proteins (includingTnfa, Mcp1, inos, Il1b) in BMDM transfected withsiScramble, whereasMdm2silencing largely abrogated these pro-inflammatory responses (Fig.1c–g). Consistently, ...