profilaggrin profilaggrin(profilaggrin) CAS: 化学式: 主页 产品 profilaggrin 中文名profilaggrin 英文名profilaggrin 英文别名profilaggrin
1985. Profilaggrin, a high- molecular-weight precursor of filaggrin in human epidermis and cultured keratinocytes. J. Invest. Dermatol. 85:507-512.Fleckman P, Dale BA, Holbrook KA. Profilaggrin, a high-molecular-weight pre- cursor of filaggrin in human epidermis and cultured keratinocytes. J ...
The profilaggrin molecule (Figure 2) is composed of an N-terminal domain, which has calcium-binding and nuclear localization components, followed by 10, 11, or 12 nearly identical filaggrin repeats, which have keratin-binding properties, plus a C-terminal domain of unknown function (Sandilands ...
求翻译:profilaggrin是什么意思?待解决 悬赏分:1 - 离问题结束还有 profilaggrin问题补充:匿名 2013-05-23 12:21:38 profilaggrin 匿名 2013-05-23 12:23:18 profilaggrin 匿名 2013-05-23 12:24:58 profilaggrin 匿名 2013-05-23 12:26:38 profilaggrin 匿名 2013-05-23 12:28:18 pro...
Profilaggrin (ProFG) is a precursor protein that must be proteolytically processed to filaggrin which aggregates keratin filaments in the stratum corneum of the skin. Human ProFG consists of 10-12 filaggrin domains linked to an N-terminus with distinct A and B domains. Previous studies from our...
We also subjected profilaggrin to protein phosphatase 2A treatment and measured its subsequent solubility. We found that granular morphology is not dependent on the linker or conserved phosphorylation sites, nor is solubility affected by protein phosphatase 2A treatment. Granule morphology was abrogated ...
Analysis of profilaggrin processing in keratinocyte air-liquid cultures transfected with siRNA against POMP.Johanna DahlqvistHans TörmäJitendra BadhaiNiklas Dahl
The transitional cells between the granular and cornified cells show morphologic characteristics of apoptotic cells, and their nuclei contain fragmented DNA and profilaggrin N-terminal domains. This suggests that the N-terminus of profilaggrin may participate in nuclear events accompanying programmed cell...
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PROBLEM TO BE SOLVED: To provide a novel antibody specific to a profilaggrin C-terminal domain that is important in keratinization of a keratin fiber of a granular layer of epidermis, a method for detecting the abnormality of a filaggrin gene where the antibody is used, and a kit for the ...