白细胞介素-2（interleukin-2,IL-2）又称“T细胞生长因子(TCGF)”、“T细胞刺激因子(TSF)”等，主要产生于 T 细胞，B 细胞和 NK 细胞中也会产生部分 IL-2。IL-2对T淋巴细胞有促分化和促增殖的作用，发挥该细胞的杀伤能力，还可以激活杀伤肿瘤细胞的LAK 和TIL 细胞，增强杀伤活性，同时诱导 T细胞和 NK 细...
PeproTech 研究级蛋白不仅包含细胞因子,还包含重组生长因子、趋化因子、神经营养因子、蛋白酶、其他酶、配体和受体。特征明确的生长因子是开发类器官作为体外疾病模型的关键组成部分。 大多数 PeproTech 重组蛋白基于人、小鼠和大鼠的天然序列,并在细菌、哺乳动物或昆虫细胞中进行生产。大多在大肠杆菌中生产的 PeproTech...
Kobayashi Y (2010) The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation. J Leukoc Biol 88(6):1157–1162. https://doi.org/10.1189/jlb.0310149 Article PubMed CAS Google Scholar Antonioli L, Csoka B, Fornai M, Colucci...
IL-2改造新策略:前药技术 著名的华人科学家,德克萨斯大学西南医学中心免疫学系的傅阳心在Nature Communications发表他们的结果,开发了一种IL-2前药技术ProIL2(cytokine receptor-masked IL2 prodrug)。 药物设计思路 为了使IL-2优先靶向半衰期长的肿瘤浸润淋巴细胞(TILs),ProIL2具有四个结构域:人类IgG1、一个IL-2变体...
Others About us Welcome To Our Site! PeproTech was established in 1988 by a group of scientists who decided to focus their efforts on the development and production of recombinant cytokines for life-science research. Today, PeproTech is a world leader in supplying high quality cytokine products...
人细胞因子/趋化因子/生长因子便利 45-Plex ProcartaPlex 检测组合 1 可通过使用 Luminex xMAP 技术在单个孔中分析 45 种蛋白靶标来研究免疫功能。该检测组合以即用型形式提供,配有以 1X 的浓缩倍数配制的一样品瓶捕获和检测试剂,所需的移液和实验设置更少。相同靶标可在人细胞因子/趋化因子/生长因子 45-Plex...
Tzeng A et al. Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3320-5. Cao X et al. Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance. Nat...
User Guide: ProcartaPlex Canine Cytokine Chemokine Growth Factor Panel 1 11-Plex Cookie设置 我们及我们的关联方等通过运用Cookie等技术来为您提供您感兴趣的网站定制内容、识别访问者、保障安全登录和收集数据。点击“全部接受”以接受所有 cookie 并直接跳转至网站,或点击“管理设置”以查看 cookie 类型的详细说明...
Cat#CytokineDescriptionPromotion SKU 10772-H02HAdiponectinAdiponectin Protein, Human, Recombinant (hFc Tag)100µg 50636-M08HAdiponectinAdiponectin Protein, Mouse, Recombinant (His Tag)100µg 50300-M07HAngiopoietin-1Angiopoietin-1 Protein, Mouse, Recombinant (His Tag)100µg ...
Proinflammatory Cytokine Systemic Inflammatory Response Syndrome Multiple Organ Dysfunction Syndrome Endotoxic Shock These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves. ...