Pro-inflammatory cytokine mRNA levels were quantified through qPCR. Results: We observed higher expression of pro-inflammatory cytokine genes (IL-1A, IL-1B, IL-6, INF-γ, TGF-β) in penile cancer tissue. The average follow-up period was 48 months (range: 38–54 months...
the locus also harbors a number of genes encoding proteins in the interleukin 1 family of pro-inflammatory cytokines. It is well-established that IL-1 signaling plays a central role in the process leading to parturition in healthy term pregnancies42. However, infections or ...
The presence of a microglia-rich microenvironment and the expression of inflammatory cytokines has been related to the mesenchymal transformation of high-grade glioma tumor stem cells under reduced oxygen levels and other cellular stresses21,38. To assess if a similar mechanism could underlie the gener...
length; what remains to be considered is how these cytokine- orchestrated immune responses influence Nm and modulate virulence gene expression and phenotype. Here, we investi- gate the bacterial mechanisms employed to respond to this inflammatory reaction and phenotypic change independently ...
The aim of this study was to explore the associations between common potential functional promoter polymorphisms in pro-/anti-inflammatory cytokine genes and kidney function/chronic kidney disease (CKD) prevalence in a large Japanese population. A total
IL- 1 是重要的前炎性细胞因子(pro-inflammatory cytokine),能强力抑制胃酸的分 泌,导致低胃酸症。 • Furuta等 [2] 报道Hp感 …www.docin.com|基于19个网页 2. 炎性细胞激素 ...- Kappa B, NF-kB)的活性,进而抑制炎性细胞激素(pro-inflammatory cytokine)的分泌,如:TNF-, IL-1, IL-6等;baik...
miR-148a mimic and significantly increased in NP cells transfected with miR-148a inhibitor (Fig. 3). These results indicated that miR-148a inhibits pro-inflammatory cytokine levels in LPS-stimulated NP cells. This suggests that miR-148a may inhibit pro-inflammatory factors released by IVD cells...
The Pro-Inflammatory Cytokine Cascade J.-M. Cavaillon and M. Adib-Conquy Introduction The production of pro-inflammatory cytokines is a prerequisite for initiating the anti-infectious process, whereas their exacerbated production during severe in- flammation may contribute to deleterious consequences. ...
Pro-inflammatory cytokine profile in dairy cows: consequences for new lactation. Ital. J. Anim. Sci. 14:3862.Trevisi E, Jahan N, Bertoni G, Ferrari A, Minuti A. Pro-inflammatory cytokine profile in dairy cows: consequences for new lactation. Ital J Anim Sci. 2015;14:285-92....
Peak-like transcriptional responses are typical for the induction of cytokine genes in immune cells to restrain deleterious inflammatory processes through potent counter- regulatory mechanisms39. Hence, this difference in the kinetics demonstrates how MITF loss overrides intrinsic negative feedbacks of ...