Extension of AlphaFold to support prediction of multimeric protein structures from sequences. Aronson, A., Hochner, T., Cohen, T. & Schneidman-Duhovny, D. Structure modeling and specificity of peptide–MHC class I interactions using geometric deep learning. Preprint at bioRxiv https://doi.org/...
Despite broad scientific interest in harnessing the power of Earth’s microbiomes, knowledge gaps hinder their efficient use for addressing urgent societal and environmental challenges. We argue that structuring research and technology developments aroun
It is known as nucleic acid interaction domain but can also contribute to protein-protein interactions [13–16]. The classical zinc finger fold consists of an approximately 30-amino acid unit of two antiparallel β strands linked to an amphipathic α-helix with two cysteines and two histidines ...
Communication between these lymphocytes occurs via two major modalities: secretion of soluble proteins such as cytokines and chemokines and surface ligand-receptor interactions. These signals alter the functional state of the receiving (and sometimes the sending) cell. Collectively, these cell populations,...
Furthermore, the increasing of the slope of the lasing threshold curve and the narrowing of the spectral linewidth occur simultaneously during the lasing state. As a result, the sensitivity and resolution are improved, and then the detection limit is lowered when micro- and nano-lasers are ...
For starters,eat something (sensible).Studies have shown that a dose of glucose restores willpower and the ability to make better, well-thought-out decisions. In other words, a healthy snack with a bit of protein can reset the brain, and give you the boost of energy you need to stay c...
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the most rapid vaccine development in history, with mRNA vaccines at the forefront
The human microbiome is a complex and dynamic system that plays important roles in human health and disease. However, there remain limitations and theoretical gaps in our current understanding of the intricate relationship between microbes and humans. In
For starters,eat something (sensible).Studies have shown that a dose of glucose restores willpower and the ability to make better, well-thought-out decisions. In other words, a healthy snack with a bit of protein can reset the brain, and give you the boost of energy you need to stay ca...