The chapter describes the basic principles, advantages, limitations, protocols and applications of FISH. In addition, troubleshooting of FISH has been also described here. Comparative genomic hybridization (CGH) provides the information on global view of gain or loss of chromosome of the tumor genome...
which is a specific feature of all mammals. In humans, ~90% of the cerebral cortex is neocortex. Over the course of evolution, the human cerebral cortex attained the largest number of neurons among primates (16.3 billion), which is thought to be the dominant contributor to underlying human i...
What is selectivity in analytical chemistry? What is sampling in analytical chemistry? What is a laboratory observation? What is morphometric analysis in situ hybridization? What is the "do no harm" principle? What are the principles of stratigraphy? What is functional analysis in engineering? What...
The sensing principle and its performance is described in (Basuray et al., 2009). The sensor consists of interdigitated electrodes integrated into a flow cell (Fig. 2). Carbon nanotubes (CNTs) are functionalized with capture probes for the hybridization of target NAs. The electrodes are used...
Multiplex PCRmultiplies several fragments in a single DNA sample by using a number of primers. Long-range PCRuses a variety of polymerases, to generate larger DNA ranges. In situ PCRis a type of PCR that occurs in cells or fixed tissue on a slide ...
Bond lengths between atoms of P–Ga co-doped graphene Bond typesBond lengths (Å) C1–Ga 1.72 C2–Ga 1.72 C3–P 1.64 C4–P 1.64 P–Ga 1.95 Table 1 shows us very visually the bond lengths between the P and Ga atoms doped into graphene in situ. The bond length of the covalent bo...
The interaction of exciton-plasmon coupling and the conversion of exciton-plasmon-photon have been widely investigated experimentally and theoretically. In this review, we introduce the exciton-plasmon interaction from basic principle to applications. Th
in-situ DNA hybridizationWe report the development of the first automated method for immunocytochemistry using the Code-On Immunology System, an IBM System II driven triaxial robotic slide staining unit. The system uses a unique capillary action design to apply, incubate, and sequentially remove ...
The chapter describes the basic principles, advantages, limitations, protocols and applications of FISH. In addition, troubleshooting of FISH has been also described here. Comparative genomic hybridization (CGH) provides information on a global view of the gain or loss of chromosomes of the tumour ...
mRNA in situ hybridizationPrevious research has identified methodological problems in the design and conduct of randomized trials that could, if left unaddressed, lead to biased results. In this report we discuss one such problem, inadequate control intervention, and argue that it can be by far...