Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, is a chronic disease of the liver, presumably autoimmune in nature, that leads to progressive cholestasis through intrahepatic bile duct destruction [1] and often end-stage liver disease (see the image below). The name...
原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其病变由自身免疫异常引起,最终可能进展为肝硬化和肝衰竭,该病具有遗传倾向。本文主要的参考文献为中华医学会肝病学分会《2021原发性胆汁性...
Primary biliary cholangitis (PBC, formerly known as primary biliary cirrhosis) is an uncommon cholestatic liver disease characterized by immune-mediated destruction of biliary epithelial cells. PBC is female preponderant and typically presents in the fifth or sixth decade of life. The clinical presentat...
原发性胆汁性胆管炎(primary biliary cholangitis, PBC) 前言:原发性胆汁性胆管炎(primary biliary cholangitis,PBC)以前称为原发性胆汁性肝硬化(primary biliary cirrhosis,PBC),是一种以肝内小胆管损伤和胆汁淤积为特点的自身免疫性肝病,其...
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease of autoimmune etiology characterized by inflammation and progressive destruction of the small intrahepatic bile ducts. The disease develops due a combination of a genetic predisposition and environmental and possibly infectious triggers...
网络原发性胆汁性胆管炎 网络释义 1. 原发性胆汁性胆管炎 ...ry Biliary Cirrhosis)应改名为原发性胆汁性胆管炎(Primary Biliary Cholangitis),两者的缩写都是PBC。 blog.sina.com.cn|基于 1 个网页
Notably, the diversity of the intestinal microbiome is diminished in individuals with primary biliary cholangitis. The intricate interplay among immune cells, cytokines, chemokines, and biliary epithelial cells is postulated as the underlying pathogenic mechanism involved in the development and progression ...
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by biliary destruction, progressive cholestasis, and potentially liver cirrhosis. Patients develop a well-orchestrated immune reaction, both innate and adaptive, against mitochondrial antigens that specifically targets intrahepatic bi...
Primary biliary cholangitis (PBC) is an autoimmune liver disease. The aetiology of PBC remains unclear, and its pathogenesis is complex. Animal models are essential to clarify the pathogenesis of PBC and explore the occurrence of early events. Herein, we
PBC: Primary biliary cholangitis, is marked by slow progressive destruction of the intrahepatic bile ducts, which leads to cirrhosis. Experiences and lessons In patients with PBC, it is necessary to check up not only liver function but also carcinogenesis including HCC, CCC and cHCC-CCC. ...