Wong-Brown MW, Meldrum CJ, Carpenter JE, Clarke CL, Narod SA, Jakubowska A, Rudnicka H, Lubinski J, Scott RJ: Prevalence of BRCA1 and BRCA2 germline mutations in patients with triple-negative breast cancer. Breast Cancer Res Treat. 2015;150(1):71-80....
Breast cancer in young women (YBC): prevalence of BRCA1/2 mutations and risk of secondary malignancies across diverse racial groups. Ann Oncol 2009; 20: 1653-1659. http://dx.doi.org/10.1093/annonc/mdp051Haffty BG, Choi DH, Goyal S, Silber A, Ranieri K, Matloff E, Lee MH, Nissen...
Prevalence and predictors of BRCA1/BRCA2 mutations in a population-based study of breast cancer in 2318 Caucasian and African-American women. Background: Although well studied in high-risk families, the prevalence and predictors of mutations in the cancer susceptibility genes, BRCA1 and BRCA2, ...
Nine of the 136 (6.6%) were found to carry BRCA deleterious mutations (MUT) (1 BRCA1 and 8 BRCA2), and 20 were detected with rare BRCA variants of unknown significance (UV). Both MUT and US BRCA alterations were more frequent in younger patients: 7 (11.6%) MUT and 12 (19.3%) UV...
BRCA2MutationChinese womenFamilial breast cancer0.005; =0.01, respectively). In addition, both =0.001; =0.01). Our study suggested that the spectrum and characteristics of BRCA1/2 mutations in Chinese familial breast cancer exhibit some unique features, and Chinese women with familial breast cancer...
Breast cancer in young women (YBC): prevalence of BRCA1/2 mutations and risk of secondary malignancies across diverse racial groupsBreast cancer in young women (YBC): prevalence of BRCA1/2 mutations and risk of secondary malignancies across diverse racial groupsBackground: Despite significant differe...
Pathogenic variants in BRCA1 and BRCA2 (BRCA1/2) lead to increased risk of breast, ovarian, and other cancers, but most variant-positive individuals in the general population are unaware of their risk, and little is known about prevalence in non-European
Prevalence ofBRCA1andBRCA2germline mutations in young breast cancer patients: A population-based study Sanjose,S,Leone,M,Berez,V.Prevalence of BRCA1 and BRCA2 germline mutations in young breast cancer patients: a population-based study. International ... Silvia,de,Sanjosé,... - 《...
Nine of the 136 (6.6%) were found to carry BRCA deleterious mutations (MUT) (1 BRCA1 and 8 BRCA2), and 20 were detected with rare BRCA variants of unknown significance (UV). Both MUT and US BRCA alterations were more frequent in younger patients: 7 (11.6%) MUT and 12 (19.3%) UV...
Breast Cancer Res Treat 100(1):83–91. : 10.1007/s10549-006-9225-9Novel BRCA1 and BRCA2 germline mutations and assessment of mutation spec-trum and prevalence in Italian breast and/or ovarian cancer families (J). Giannini G,Capalbo C,Ristori E et al. Breast Cancer Research . ...