Signaling from the pre-BCR is critical for the transition to the next stage in B cell development, although there is no singular model of the pre-BCR engagement. An important insight into pre-BCR biology is provided by a recently resolved structure of a human pre-BCR. Dissection of several...
下列关于pre-BCR的说法正确的是A.pre-BCR由SLC和IgH构成B.pre-BCR可以分泌到细胞外C.pre-BCR在immature B细胞阶段才能表达D.pre-BCR没有功能的答案是什么.用刷刷题APP,拍照搜索答疑.刷刷题(shuashuati.com)是专业的大学职业搜题找答案,刷题练习的工具.一键将文档转化为在线
2. Zhang M,et al.2004.Cell Mol Immunol.1:89. Gene ID 613View all products for this Gene ID UniProt View information about Pre-BCR on UniProt.org 我要询价 *联系方式: (可以是QQ、MSN、电子邮箱、电话等,您的联系方式不会被公开) *内容:...
New insights into pre-BCR and BCR signalling with relevance to B cell malignancies. Nat Rev Immunol. 2013; 13(8):578-91. https://doi.org/10.1038/nri3487 PMID: 23883968.R.C. Rickert, New insights into pre-BCR and BCR signalling with relevance to B cell malignancies, Nat. Rev. Immunol...
At this pre-BII cell stage, the IL-7Ralpha is also expressed. Some in vitro studies suggest that pre-BCR-dependent expansion relies on the IL-7Ralpha, and others that it does not. It has also been suggested that the pre-BCR mediates down-regulation of the IL-7Ralpha. However, the in...
BCR, bypassing the requirement for a pre-BCR. To address this question as a proof of principle, we examined FL B cells from mice that are deficient for a component of SLC, lambda5 (Igll1−/−), in conjunction with a transgene that has a prearranged functional heavy chain (B1.8)....
The developmental progression from pro-B to pre-B cells is controlled by pre-B cell receptor (pre-BCR) signaling which depends on BLNK (SLP-65) for coupling the Syk kinase to its downstream effector pathways. Here we identified BLNK as a direct target of the transcription factor Pax5 (BSAP...
英文名称: BD Horizon BV421 Mouse Anti-Human Pre-BCR 英文同义词: BD Horizon BV421 Mouse Anti-Human Pre-BCR CAS号: 分子式: 分子量: 0 EINECS号: 信息错误报告 您的Email: 按国家浏览BD Horizon BV421 Mouse Anti-Human Pre-BCR国外供应商 中国供应商 BD Horizon BV421 Mouse Anti-Human Pre...
替代性 BCR 复合物: BCR 复合物开始表达于不成熟 B 细胞。在 pre-B 细胞阶段, Ig 的 μ基因已完成重排,尽管 Ig 轻链基因重排尚未完成,但由于其它基因编码了假轻链。 μ链、假轻链与 Ig α/Ig β一 相关知识点: 试题来源: 解析 阴性选择:是指经阳性选择后存活的的单阳性( SP)胸腺细胞,在皮髓质交界处...
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