单细胞分析pre-B 型急性淋巴细胞白血病的骨髓微环境 文章题目:The bone marrow microenvironment of pre‑B acute lymphoblastic leukemia at single‑cell resolution日期:2020年11月 期刊:Scientific reports 数据:GSE148115 链接:https://www.nature.com/articles/s41598-020-76157-4#article-info 摘要: 骨髓微环...
必应词典为您提供pre-bcell的释义,网络释义: 前B细胞;体细胞;
Pre-B cell leukemia associated with chromosome translocation 1;19. Blood . 1984;63(3):721–724. View this article via:Carroll AJ, Crist WM, Parmley RT, Roper M, Cooper MD, Finley WH. Pre-B cell leukemia associated with chromosome translocation 1;19. Blood. 1984;63(3):721-724....
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Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2) (C-Term) 抗体 公司简介 上海钰博生物科技有限公司是2012年5月由“海归”组成的创业团队与两个专业投资机构发起成立的,以开发生产科研试剂和特色检验产品为方向,经过两年多的努力,已经建立了免疫学和分子生物学的五个技术平台,开发了ELISA/ELISpot酶联免疫试剂盒...
We demonstrate that, as BM cells progress from the pre-BI to large pre-BII-cell stage, there is a shift from bi- to mono-allelic λ5 transcription, while the second allele is silenced in small pre-BII cells. A VpreB1-promoter-driven transgene shows the same pattern, therefore suggesti...
Conversely, HNRPDL silencing inhibited colony-forming cell (CFC) production of CML CD34cells and attenuated BCR-ABL induced leukemia. In addition, HNRPDL modulated imatinib response of K562 cells and HNRPDL silencing sensitized CML CD34cells to imatinib treatment. Mechanistically, we found the ...
Chromosome banding studies on 60 children with acute lymphocytic leukemia (ALL), including “null,” pre-B, B, and T cell phenotypes, were performed. In 4 of 17 patients with pre-B cell ALL, we noted a previously undescribed chromosome translocation, t(1;19)(q23;q13). This translocation...
Pre-B Cell Leukemia Homeobox 1is a novel susceptibility gene that regulate T cell functions. (123.2) Pre-leukemia homeobox (Pbx) 1 is a novel lupus susceptibility gene that regulates T cell activation and tolerance in both the NZM2410 lupus-prone mouse model and lupus patients. Lupus susceptib...
Early B cell development faces a critical checkpoint at the pro-B --> pre-B transition stage, at which proper assembly and surface expression of an immunoglobulin heavy chain is somehow signaled by the pre-B cell receptor. Triggering of this signal might not require exogenous ligands....