单细胞分析pre-B 型急性淋巴细胞白血病的骨髓微环境 文章信息 文章题目:The bone marrow microenvironment of pre‑B acute lymphoblastic leukemia at single‑cell resolution日期:2020年11月 期刊:Scientific reports 数据:GSE148115 链接:https://www.nature.com/articles/s41598-020-76157-4#article-info 摘要:...
The subtype of pre-B cell acute lymphoblastic leukemia (ALL) which in childhood appears to confer an unfavorable prognosis, may have the same significance in neonatal ALL.doi:doi:10.1046/j.1537-2995.1983.23684074284.xC M SpierC R Kjeldsberg...
骨髓微环境 (bone marrow microenvironment,BMM) 在白血病进展中起关键作用,但其在pre-B 细胞急性淋巴细胞白血病 (B-ALL)(儿童最常见的癌症)中的分子复杂性仍知之甚少。为了进一步了解,本文使用单细胞 RNA 测序来表征 B-ALL 进展过程中鼠 BMM 的变化。发现pre-B 细胞在疾病的早期阶段受影响最大,这与受 AP1 转...
acute lymphoblastic leukemiaThis case provides evidence for a phenotypic switch from a characteristic T-ALL into a typical pre-B ALL. A 17 years old boy presented with massive hepatosplenomegaly and a mediastinal mass. The blasts were characterized as L2 type according to the French, American and...
Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complet... Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease ...
(FISH) tested specific genotypes and copy number aberrations of the locus in 365 children with AL.Results Specific subtypes were identified in 175 patients with B-cell precursor acute lymphoblastic leukemia (Pre-B ALL) and 54 patients with acute myeloid leukemia(AML).Among PreB ALL cases,high ...
Human homolog of murine double minute 2 (HDM2) and HDM4 (or HDMX) are negative regulators of p53. HDM4 has not been assessed in precursor B (pre-B) lymphoblastic leukemia (ALL). We examined bone marrow samples obtained at time of diagnosis from 55 adults
Bone marrow niche-derived extracellular matrix-degrading enzymes influence the progression of B-cell acute lymphoblastic leukemia ArticleOpen access09 January 2020 Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease ...
[6] Kong Y, Zhao S, Tian H, Hai Y. GAS2 Promotes Cell Proliferation and Invasion and Suppresses Apoptosis in Pediatric T-Cell Acute Lymphoblastic Leukemia and Activates Wnt/β-Catenin Pathway. Onco Targets Ther. 2020 Feb 5;13:1099-1108. ...
OUMS-27细胞类似产品::KYSE270细胞、H774细胞、B-cell Acute Lymphoblastic Leukemia-1细胞 SW-1417细胞类似产品::Jurkat FHCRC细胞、NCI-H889细胞、JURKAT E-6.1细胞 LNCaP C4-2B细胞类似产品::EB1细胞、HCE细胞、MAD109细胞 COLO394细胞类似产品::373 MG细胞、BE2-M17细胞、RGM1细胞 ...